Relationship: Brain and vitamin B12

Evidence supporting the use of: Vitamin B12
For the body system: Brain

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B12 (cobalamin) is a water-soluble vitamin that plays a crucial role in neurological function and brain health. Deficiency in vitamin B12 is well-established as a cause of neurological and psychiatric symptoms, including memory loss, cognitive decline, neuropathy, and even dementia. Scientific studies have shown that B12 is essential for maintaining the myelin sheath that surrounds and protects nerve fibers, and it is necessary for the synthesis of neurotransmitters involved in memory and mood regulation. Randomized controlled trials and observational studies indicate that low B12 levels are associated with poor cognitive performance and an increased risk of neurodegenerative disorders, especially in older adults. Supplementation with B12 can reverse neurological symptoms in cases of deficiency, and some evidence suggests that it may help slow the progression of cognitive decline in individuals with subclinical deficiency. However, in people with normal B12 levels, supplementation has not consistently shown cognitive benefits. Overall, the use of vitamin B12 to support the brain and nervous system is justified by strong scientific evidence, particularly for preventing and treating deficiency, though its benefit in non-deficient populations remains less clear.

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Other body systems supported by vitamin B12

Blood
Brain
Dopamine
Gastrointestinal Tract
Hair
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Evidence supporting the use of: Vitamin B12
For the body system: Brain

Table of Contents

Synopsis

Other ingredients that support Brain

Health Concerns

Brands

Evidence supporting the use of: Vitamin B12For the body system: Brain

Table of Contents

Synopsis

Other ingredients that support Brain

Other body systems supported by vitamin B12

Products containing vitamin B12

Evidence supporting the use of: Vitamin B12
For the body system: Brain