Relationship: Cancer Treatment (reducing side effects) and niacinamide (vitamin B3)

Evidence supporting the use of: Niacinamide (vitamin B3)
For the health condition: Cancer Treatment (reducing side effects)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Niacinamide (vitamin B3) has some scientific support for use as an adjunct in cancer treatment, primarily for the purpose of reducing certain side effects of cancer therapies. Research, especially from the 1980s and 1990s, has shown that niacinamide, often in combination with other agents like carbogen (a mixture of oxygen and carbon dioxide), can enhance the effectiveness of radiotherapy by improving tumor oxygenation. This improved oxygenation can make cancer cells more susceptible to radiation, potentially allowing for lower doses and thus reducing treatment-related toxicity.

In addition to its radiosensitizing properties, niacinamide has also been investigated for its ability to reduce specific side effects such as radiation-induced skin damage and mucositis. Some small clinical studies and animal models suggest that niacinamide may help protect normal tissues during cancer treatment by supporting DNA repair and reducing inflammation.

However, while these findings are promising, the overall clinical evidence is moderate and not yet robust enough to make niacinamide a standard therapy for reducing side effects in cancer treatment. Most guidelines do not routinely recommend it for this purpose outside of clinical trials. Patients considering niacinamide supplementation during cancer therapy should consult their oncologist, as high doses can have adverse effects and may interact with other treatments.

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Other health conditions supported by niacinamide (vitamin B3)

Acne
Age Spots
Alzheimer's Disease
Arthritis
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cholesterol (high)
Circulation (poor)
Dermatitis
Diabetes
Hair (loss or thinning)
Inflammation
Liver Detoxification
Memory and Brain Function
Psoriasis
Wounds and Sores

Products containing niacinamide (vitamin B3)

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Evidence supporting the use of: Niacinamide (vitamin B3)
For the health condition: Cancer Treatment (reducing side effects)

Table of Contents

Synopsis

Other ingredients used for Cancer Treatment (reducing side effects)

Other health conditions supported by niacinamide (vitamin B3)

Products containing niacinamide (vitamin B3)

Health Concerns

Brands

Evidence supporting the use of: Niacinamide (vitamin B3)For the health condition: Cancer Treatment (reducing side effects)

Table of Contents

Synopsis

Other ingredients used for Cancer Treatment (reducing side effects)

Other health conditions supported by niacinamide (vitamin B3)

Products containing niacinamide (vitamin B3)

Evidence supporting the use of: Niacinamide (vitamin B3)
For the health condition: Cancer Treatment (reducing side effects)