Relationship: Diabetes and vitamin B12

Evidence supporting the use of: Vitamin B12
For the health condition: Diabetes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin B12 is not used to treat diabetes itself, but there is scientific support for its use in managing a complication commonly associated with diabetes: diabetic neuropathy. People with diabetes, especially those on long-term metformin therapy (a first-line oral medication for type 2 diabetes), are at increased risk for vitamin B12 deficiency. Metformin has been shown to interfere with B12 absorption, leading to deficiency in 5-10% of patients. Vitamin B12 deficiency can cause or worsen peripheral neuropathy, which is already a common complication in diabetes.

Several clinical guidelines recommend monitoring B12 levels in diabetic patients on metformin and supplementing when deficiency is detected. Randomized controlled trials and meta-analyses support that B12 supplementation can improve neuropathic symptoms and prevent progression of deficiency-induced neurological damage. However, there is no evidence that B12 supplementation directly lowers blood glucose or treats diabetes itself. The use of B12 is thus evidence-based for a diabetes-related complication, not the underlying disease.

In summary, while vitamin B12 is not a treatment for diabetes, its supplementation is scientifically validated to prevent or address neuropathy in diabetic patients, particularly those taking metformin. The overall evidence level is moderate (rated 3/5), mainly for neuropathy prevention and management, not for glycemic control.

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Evidence supporting the use of: Vitamin B12
For the health condition: Diabetes

Table of Contents

Synopsis

Other ingredients used for Diabetes

Other health conditions supported by vitamin B12

Products containing vitamin B12

Health Concerns

Brands

Evidence supporting the use of: Vitamin B12For the health condition: Diabetes

Table of Contents

Synopsis

Other ingredients used for Diabetes

Other health conditions supported by vitamin B12

Products containing vitamin B12

Evidence supporting the use of: Vitamin B12
For the health condition: Diabetes