Relationship: Fat Metabolism (poor) and choline

Evidence supporting the use of: Choline
For the health condition: Fat Metabolism (poor)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Choline is an essential nutrient that plays a significant role in fat metabolism, particularly in the liver. It is a precursor for phosphatidylcholine, a key component of very-low-density lipoproteins (VLDL) that are needed to export triglycerides from the liver. Without adequate choline, fat can accumulate in the liver, potentially leading to nonalcoholic fatty liver disease (NAFLD). Scientific studies in both animals and humans have demonstrated that choline deficiency results in impaired hepatic lipid export and subsequent fatty liver. For example, controlled human studies have shown that low-choline diets can induce signs of fatty liver and liver dysfunction, which are reversible upon choline repletion (Zeisel & da Costa, 2009).

While choline supplementation is clearly effective in preventing and treating choline-deficiency-induced fatty liver, evidence for its use in treating general "poor fat metabolism" in the absence of a deficiency is less robust. Some clinical trials suggest possible benefits of choline supplementation on liver health in specific populations, but there is limited evidence that it enhances overall fat metabolism or weight loss in healthy individuals. Therefore, its use is scientifically justified in the context of choline deficiency or certain liver conditions, but broad benefits for fat metabolism are less well-established. Overall, choline's role in fat metabolism is supported by a moderate level of clinical evidence, particularly for liver health.

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Other ingredients used for Fat Metabolism (poor)

3-desoxy-7-KETO-DHEA
7-Keto-DHEA
Acetyl L-carnitine
Alpha methyl tetradecylthioacetic acid
alpha-linolenic acid (ALA)
AMP-activated protein kinase (AMPK)
anchovies
apple cider vinegar
artichoke
avocado
barberry
Berberis (unspecified)
beta-hydroxybutyrate
bile salt
biotin
black ginger
capric acid
capsaicin
capsaicinoids
capsiate
capsinoids
cardarine
carqueja
cha de bugre
chia seed
choline
cinnamon
coconut oil
Coleus forskohlii
conjugated linoleic acid (CLA)
coriander
dandelion
diacylglycerol
dihydrocapsiate
ephedrine
epigallocatechin gallate (EGCG)
evodiamine
fenugreek
flavanones
flavonols
forskohlii root
forskolin
fucoxanthin
garcinia
ginger
glucomannan
grains of paradise
guggul
gymnemic acids
hesperetin
Higenamine
hydroxycitric acid
isomaltulose
kelp
l-carnitine
lecithin
Legume protein
linoleic acid (LA)
lipase
lipstatin
macadamia
medium chain triglycerides (MCT)
Milk thistle
Monounsaturated fat
Oleoylethanolamide
omega-3 fatty acids
omega-7 fatty acids
oolong tea
Palatinose
palmitate
pantethine
Perperine
phaseolamin
phospholipids
Pinolenic acid
polyphenols
Rauwolscine
robusta coffee
Synephrine
Tetradecylthioacetic acid
Thylakoid
turmeric
Ursolic Acid
vitamin B
Wakame
Walnut
Yohimbine
Zinc

Other health conditions supported by choline

Alzheimer's Disease
Autism
Birth Defects (prevention)
Cardiovascular Disease
Depression
Fat Metabolism (poor)
Fatty Liver Disease
Memory and Brain Function
Pregnancy (herbs and supplements for)
Triglycerides (high)

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Evidence supporting the use of: Choline
For the health condition: Fat Metabolism (poor)

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Synopsis

Other ingredients used for Fat Metabolism (poor)

Other health conditions supported by choline

Products containing choline

Health Concerns

Brands

Evidence supporting the use of: CholineFor the health condition: Fat Metabolism (poor)

Table of Contents

Synopsis

Other ingredients used for Fat Metabolism (poor)

Other health conditions supported by choline

Products containing choline

Evidence supporting the use of: Choline
For the health condition: Fat Metabolism (poor)