Relationship: Gastrointestinal Tract and thiamin (vitamin B1)

Evidence supporting the use of: Thiamin (vitamin B1)
For the body system: Gastrointestinal Tract

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Source of validity: Scientific
Rating (out of 5): 3

Thiamin (vitamin B1) is an essential water-soluble vitamin that plays a critical role in carbohydrate metabolism and energy production. Its relevance to the gastrointestinal (GI) tract is supported by scientific evidence, particularly in the context of deficiency states. Thiamin is necessary for the proper functioning of several enzymes involved in energy metabolism, which is vital for the high-energy demands of the GI tract’s smooth muscle and mucosal cells. Deficiency in thiamin can lead to gastrointestinal symptoms such as anorexia, constipation, and abdominal discomfort. Severe deficiency, as seen in beriberi and Wernicke-Korsakoff syndrome, can manifest with GI complaints in addition to neurological and cardiovascular symptoms. Supplementation with thiamin is well established in the treatment and prevention of these deficiency-related GI symptoms.

However, outside of deficiency states, there is limited evidence supporting thiamin supplementation specifically to enhance or directly support GI tract health in healthy individuals. Most clinical use is based on its necessity for maintaining normal GI function rather than having a therapeutic role in common GI diseases. Historical and clinical data justify its inclusion for individuals at risk of deficiency—such as those with chronic alcoholism, malnutrition, or malabsorption syndromes—but not for general GI health support in the absence of deficiency. Therefore, while the use of thiamin for the gastrointestinal tract is scientifically validated in deficiency, routine supplementation for GI support in well-nourished individuals is not strongly substantiated.

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Evidence supporting the use of: Thiamin (vitamin B1)
For the body system: Gastrointestinal Tract

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Synopsis

Other ingredients that support Gastrointestinal Tract

Other body systems supported by thiamin (vitamin B1)

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Evidence supporting the use of: Thiamin (vitamin B1)For the body system: Gastrointestinal Tract

Table of Contents

Synopsis

Other ingredients that support Gastrointestinal Tract

Other body systems supported by thiamin (vitamin B1)

Products containing thiamin (vitamin B1)

Evidence supporting the use of: Thiamin (vitamin B1)
For the body system: Gastrointestinal Tract