Relationship: Nerves and pantothenic acid (vitamin B5)

Evidence supporting the use of: Pantothenic acid (vitamin B5)
For the body system: Nerves

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Pantothenic acid (vitamin B5) is an essential water-soluble vitamin that plays a critical role in energy metabolism, primarily as a component of coenzyme A, which is involved in the synthesis and oxidation of fatty acids. Its role in supporting the nervous system is grounded in its biochemical necessity for the synthesis of acetylcholine, a key neurotransmitter involved in nerve signal transmission. However, while its fundamental requirement for basic nervous system function is not disputed, direct evidence supporting supplemental pantothenic acid for enhanced nerve health or for treating neurological disorders is limited.

Most individuals obtain sufficient pantothenic acid from a typical diet, and deficiency in developed countries is rare. Severe deficiency can cause symptoms like numbness, tingling, and muscle cramps, which are related to nerve dysfunction. Historical reports, such as “burning feet syndrome” observed in prisoners of war with malnutrition, have been linked to pantothenic acid deficiency and resolved with supplementation. However, in healthy individuals, additional supplementation does not appear to provide extra neurological benefits beyond preventing deficiency.

In summary, while pantothenic acid is essential for normal nerve function at physiological levels, there is little scientific evidence to support its use as a supplement specifically to enhance or “support” the nervous system in individuals without deficiency.

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Other body systems supported by pantothenic acid (vitamin B5)

Adrenal Cortex
Adrenal Glands
Brain
Cortisol
Glandular System
Hair
Mitochondria
Nerves
Skin

Products containing pantothenic acid (vitamin B5)

Health Concerns

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Evidence supporting the use of: Pantothenic acid (vitamin B5)
For the body system: Nerves

Table of Contents

Synopsis

Other ingredients that support Nerves

Other body systems supported by pantothenic acid (vitamin B5)

Products containing pantothenic acid (vitamin B5)

Health Concerns

Brands

Evidence supporting the use of: Pantothenic acid (vitamin B5)For the body system: Nerves

Table of Contents

Synopsis

Other ingredients that support Nerves

Other body systems supported by pantothenic acid (vitamin B5)

Products containing pantothenic acid (vitamin B5)

Evidence supporting the use of: Pantothenic acid (vitamin B5)
For the body system: Nerves