Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Folate, also known as vitamin B9, is scientifically validated as an essential nutrient for supporting the reproductive system, particularly in women of childbearing age. Robust evidence demonstrates that adequate folate intake before and during early pregnancy is crucial for proper fetal neural tube development and significantly reduces the risk of neural tube defects (NTDs) such as spina bifida and anencephaly. These findings have led to widespread public health recommendations for folic acid supplementation among women who are planning to conceive or are pregnant. In addition to its role in neural development, folate is involved in DNA synthesis, repair, and methylation, processes vital for cell division and embryonic growth. Deficiency in folate can also lead to reproductive complications, including infertility and pregnancy loss. The Centers for Disease Control and Prevention (CDC), World Health Organization (WHO), and numerous peer-reviewed clinical trials and epidemiological studies have established the importance of folate in reproductive health. Consequently, folate fortification in foods has been implemented in many countries and has demonstrably decreased the incidence of NTDs. The scientific support for folate’s role in the reproductive system is among the strongest for any nutrient, justifying its use and recommendation for reproductive health support.

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Other ingredients that support Reproductive System

Other body systems supported by folate

Products containing folate

Thorne 5-MTHF 1 mg Folate
Thorne 5-MTHF 5 mg Folate
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Pure Encapsulations B-Complex Plus
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Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
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Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
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Pure Encapsulations VisionPro Nutrients
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Metagenics Wellness Essentials® Daily Packs
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Metagenics Wellness Essentials Men's Vitality Daily Packs
Metagenics Wellness Essentials Women's Daily Packs
Metagenics Wellness Essentials Women's Prime Daily Packs
Thorne Women's Multi 50+
Pure Encapsulations Women's Nutrients
Pure Encapsulations Women's Nutrients
Designs For Health Women's Twice Daily Essential Packets