Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Choline is a nutrient that plays a crucial role in brain health and neurotransmitter synthesis, particularly as a precursor for acetylcholine, a major neurotransmitter involved in memory, muscle control, and other nervous system functions. Scientific studies have shown that adequate choline intake is necessary for maintaining normal acetylcholine levels. Deficiency in choline can lead to cognitive impairment, as demonstrated in both animal and human studies. Supplementation with choline or its derivatives (such as citicoline or alpha-GPC) has been shown to increase acetylcholine synthesis and release, with potential benefits for memory and cognitive function, especially in older adults or those with neurodegenerative conditions. However, while the mechanistic link between choline and neurotransmitter support is well-established, clinical evidence for cognitive enhancement in healthy individuals is mixed. Nonetheless, the biological plausibility and supportive data from both basic and clinical research provide a strong scientific rationale for choline’s use in supporting the “Specific Neurotransmitters” body system, specifically through its role in acetylcholine synthesis.

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Other ingredients that support Specific Neurotransmitters

Other body systems supported by choline

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