Relationship: Stress and vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Stress

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis
Other ingredients for this health condition
Other health conditions supported by this ingredient
Products containing this ingredient

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B6 (pyridoxine) is sometimes used to support or treat stress, largely based on its role in neurotransmitter synthesis and regulation of homocysteine metabolism. Scientifically, vitamin B6 is essential for the biosynthesis of neurotransmitters such as serotonin, dopamine, and GABA, all of which are implicated in mood regulation and stress response. Several observational studies have found associations between low levels of B6 and increased symptoms of depression and anxiety, both of which are closely linked to stress. However, evidence from randomized controlled trials specifically evaluating B6 supplementation for stress reduction in healthy individuals is limited and mixed.

Some studies suggest that supplementation with B6, often in combination with other B vitamins or magnesium, may help reduce perceived stress or improve mood in certain populations, such as those with pre-existing deficiencies or premenstrual syndrome (PMS). For instance, a few trials have reported mild improvements in mood and stress levels in women with PMS when supplemented with B6. Nevertheless, these benefits are generally modest, and it is unclear whether B6 alone provides significant stress-relieving effects in the general population.

Overall, while there is a plausible biological mechanism for B6’s involvement in stress and some supportive evidence, the scientific validation is not robust, and high-quality clinical trials are lacking. Thus, the evidence supporting the use of vitamin B6 specifically for stress management is weak to moderate (rated 2/5).

More about vitamin B6
More about Stress

Other ingredients used for Stress

5-Hydroxytryptophan (5-HTP)
7-Keto-DHEA
Acetyl L-carnitine
alpha-pinene
arjun tree
ashwagandha
asparagus
astragalus
Waterhyssop
benegut perilla (proprietary)
bergamot
Bifidobacterium bifidum
Bifidobacterium lactis
Bifidobacterium longum
sesame
black tea
bonito peptide
bupleurum falcatum
California poppy
caterpillar mushroom
chaga mushroom
chamomile
cordyceps
curcumin
damiana
DHA (docosahexaenoic acid)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
GABA (gamma aminobutyric acid)
gardenia
gotu kola
green tea
guayusa
heartwood
hibiscus
hops
jujube
kava
kudzu
L-ornithine
L-taurine
L-theanine
L-tryptophan
l-tyrosine
lactium casein decapeptide
Lactobacillus brevis
Lactobacillus casei
Lactobacillus helveticus
lactiplantibacillus plantarum
lavender
Lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
magnesium
magnolia
Matcha
Melatonin
Mint
Motherwort
Muira puama
Acetyl-L-Tyrosine
oat
passionflower
Peppermint
perilla
phosphatidylserine
phospholipids
pine bark
polygala root
pregnenolone
pyrroloquinoline disodium salt
quail egg
relora® (proprietary)
Rhodiola
rose oil
saffron
sceletium
black ginger
skullcap
spearmint leaf
spinach
Valerian root
velvet bean
vitamin B12
vitamin B6
Mulberry
whole adrenal glandular
Zinc
sarsaparilla
suma
jiaogulan
catnip
cardamom
anise
Fumaria parviflora
bee pollen
lingzhi
kanna
silk tree
oriental arborvitae
anemarrhena asphodeloides
St. John's Wort
Yerba mate
noni
Wood betony
biota seed
goji berry
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
star of Bethlehem
7,8-Dihydroxyflavone
Aralia
arjuna
Akebia
antler
Agastache
Agrimony
apigenin
Antrodia camphorata
Arginine aspartate
Albizia
Anserina
Agmatine
Agarwood
Alpha lactalbumin
Algal protein
betony
Baikal Skullcap
Black spruce
baccosides
Bacopin
baicalein
Basidiomycota
banyan
brahmi
Bacopa
Buddha\'s hand
borage
banana
Bifidobacteria
Bupleurum
bacoside
baicalin
bird\'s nest
Centella triterpenes
Monkey flower
Clary sage
Chinese mountain ant
Codonopsis
coriander
Clerodendrum phlomidis
Chinese fleeceflower
chuchuhuasi
Cymbopogon martini
Calea zacatechichi
Centella asiatica
coca
chocolate
Capitate Valerian
corktree
catuaba
C-phycocyanin
cypress
cowslip
calamus
cherimoya
Convolvulus prostratus
Corydalis
Convolvulus pluricaulis
Celastrus
Canscora
dismutase
dodeca-2E, 4E-dienoic acid isobutylamide
dibenzo-alpha pyrones
devil\'s club
date
dodeca-2E, 4E, 8Z, 10Z/tetraenoic acid isobutylamide
Eplotab
Erythrina
emblicanin
Eurycoma Longifolia
fo-ti
fragrant rosewood
Ficus religiosa
fish
frankincense
flavones
goldthread
Gelsemium
Ginsenosides
Griffonia simplicifolia
gum
galactooligosaccharides
Glycine
gastrodin
Honokiol
Hemidesmus
Homalomena
Hypericum
hericium mushroom
honeybush
isoliquiritigenin
Japanese kadsura
jasmine
jujubosides
Jatamansi
kavalactones
Kukicha
kola nut
kuding tea
Lycium
lemon balm
Lactucarium
linden
Lactococcus rhamnosus
Lactucopicrin
limonene
longan
Lavandin
lotus
Leptadenia
Large-leaved linden
lupulinum
lactalbumin
Mentha haplocalyx
macamides
mandarin
maral root
mangiferin
Myrcene
Mung bean
Marjoram
Mimulus
Mistletoe
Methylxanthine
Mimosa
Meadow sage
Mate
magnolol
Mulungu
macaenes
Mesembrine
Nardostachys
Night jessamine
Nymphaea caerulea
oolong tea
orchid
Oxindole alkaloids
pyrroloquinoline quinone
Piper chaba
Patchouli oil
Pepper Bark Tree
Pentatropis capensis
Passionfruit
poppy
Pistachio
Polygala
Purple Monkeyflower
rosavins
Rosabin
Rauvolfia
Rehmannia
rose
Rooibos
Speedwell
Sumbul
Spikenard
Scleranthus annus
Salidroside
Safed musli
Sarivan
Shankhpushpi
Sweet Woodruff
Schisandrins
Sida cordifolia
Semecarpus anacardium
Stachytarpheta cayennensis
Schizandrol A
Shataverins
Sandy Everlasting
Shilajit
Safranal
Tetracyclic oxindole alkaloids
Traveler's Joy
Trichilia catigua
Taxillus chinensis
Trichopus zeylanicus
Taurine
Tagara
Tetrahydropalmatine
Uncaria
Vetiver
Valerenic acid
Vine tea
Vitexin
Viburnum
Verbena
Vanilla
Withanolides
Wogonin
Xanthine
Xanthophyll
Xylaria nigripes
Xanthone
Yuzu
Yellow-Fruit Nightshade
Yumberry
Yohimbine
Ylang ylang

Other health conditions supported by vitamin B6

Alcoholism
Amenorrhea
Anemia
Anxiety
Anxiety Disorders
Anger (excessive)
Arthritis
Attention Deficit Disorder
Autism
Bell's Palsy
Burning Feet or Hands
Carpal Tunnel Syndrome
Chemotherapy (reducing side effects)
Depression
Diabetes
Dysmenorrhea
Emotional Sensitivity
Energy (lack of)
Epilepsy
Fatigue
Hair (loss or thinning)
Hair Care (general)
Hangover
Hashimoto's Disease
Hiccups
Hot Flashes
Infertility
Inflammation
Insomnia
Irritability
Kidney Stones
Liver Detoxification
Memory and Brain Function
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Migraine
Mood Swings
Morning Sickness
Nausea and Vomiting
Nerve Damage
Nervous Exhaustion
Nervousness
Neuralgia and Neuritis
Nightmares
Numbness
Obsessive Compulsive Disorder
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Rheumatoid Arthritis
Schizophrenia
Seborrhea
Seizures
Sleep (restless and disturbed)
Sore or Geographic Tongue
Stress
Thinking (cloudy)
Tics
TMJ
Tuberculosis
Twitching
Worry

Products containing vitamin B6

Health Concerns

Brands

Evidence supporting the use of: Vitamin B6
For the health condition: Stress

Table of Contents

Synopsis

Other ingredients used for Stress

Other health conditions supported by vitamin B6

Products containing vitamin B6

Health Concerns

Brands

Evidence supporting the use of: Vitamin B6For the health condition: Stress

Table of Contents

Synopsis

Other ingredients used for Stress

Other health conditions supported by vitamin B6

Products containing vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Stress