Prostate Support | Comprehensive Health Guide

Name: Prostate Support
Brand: Vitabase
SKU: VB-931
Price: 21.95 USD
Availability: InStock

Explore how Prostate Support with Saw palmetto, Pygeum, Zinc, Pumpkin seed oil & more may promote prostate health and healthy urinary flow in men.

Overview

What Is Prostate Support and Why Does It Matter?

If you are male, you have over a 50% chance of developing serious prostate problems at some point in your life. These problems can lead to significant health concerns and may profoundly affect quality of life. Prostate Support is a softgel formula specifically designed to help with disorders of the prostate, focusing on prostate health, prostate size management, and healthy urinary flow.

Among its many ingredients, this Prostate Support formula contains high-potency Saw palmetto and Pygeum africanum standardized to 13% beta-sitosterol. This combination has been studied for its potential to help reduce prostate enlargement and support healthy urinary function. The softgel delivery format is designed to preserve the potency of the active ingredients — particularly the lipid-soluble compounds that are central to this formula's mechanism of action.

This formula is dairy free and grain free, making it accessible to men with common dietary sensitivities.

How It Works

How Prostate Support Targets Multiple Pathways

Prostate enlargement — known clinically as benign prostatic hyperplasia (BPH) — involves hormonal, inflammatory, and proliferative processes in prostate tissue. Prostate Support addresses these pathways through a combination of botanicals, phytosterols, and essential minerals that research suggests may work synergistically.

5α-Reductase Inhibition: Saw palmetto, Pumpkin seed oil, and Zinc each have research suggesting they may help regulate the enzyme 5α-reductase, which converts testosterone to dihydrotestosterone (DHT). Elevated DHT is associated with prostate tissue growth. Saw palmetto's fatty acid constituents — including lauric acid and oleic acid — have been shown in laboratory studies to inhibit both type I and type II isoforms of this enzyme.

Anti-Inflammatory Activity: Several ingredients in this Prostate Support formula, including Saw palmetto and Pygeum, have been studied for their ability to inhibit cyclooxygenase and 5-lipoxygenase pathways, which may help reduce the production of inflammation-promoting prostaglandins and leukotrienes in prostate tissue.

Prostate Cell Regulation: Zinc, which accumulates in uniquely high concentrations in healthy prostate tissue, supports apoptosis (programmed cell death) in prostate cells. Studies show that BPH and prostate cancer tissue have significantly lower Zinc levels than normal tissue. Pygeum bark extract has demonstrated antiproliferative effects on prostate fibroblasts in preclinical research.

Bladder and Urinary Tract Support: Nettle root, Pumpkin seed oil, and Saw palmetto each have clinical evidence suggesting they may support healthy urinary flow, reduce nocturia, and improve symptom scores related to lower urinary tract symptoms (LUTS) associated with BPH.

What's inside

Key Ingredients

Zinc (as monomethionine) — 5.00 mg

Zinc is an essential trace mineral required for the activity of more than 300 enzymes across all metabolic processes. The prostate gland accumulates the highest Zinc concentration of any soft tissue in the body, and studies show that Zinc levels are markedly reduced in BPH and prostate cancer tissues. Research suggests that Zinc regulates 5α-reductase activity and promotes apoptosis of prostate epithelial cells. A 2019 nutraceutical review cites Zinc as capable of producing benefits on BPH symptoms comparable to those of Lycopene, and Zinc is included in recognized BPH phytotherapy formulations alongside beta-sitosterol and selenium. Supplemental Zinc has been found in clinical practice to support urine flow and reduce residual volume in men with BPH, though large rigorous placebo-controlled trials on Zinc supplementation alone for urinary flow are limited. Zinc also plays fundamental roles in immune regulation, DNA synthesis, and hormonal interactions — including testosterone production — making it a foundational nutrient for overall male health.

Saw palmetto — 80.00 mg

Saw palmetto (Serenoa repens) is a small palm native to the southeastern United States whose dark berries have been used for centuries by Native Americans for urinary and reproductive complaints. It is one of the most extensively studied herbal remedies for BPH-associated lower urinary tract symptoms. Research suggests Saw palmetto works through multiple mechanisms: inhibition of 5α-reductase types I and II, anti-inflammatory effects via cyclooxygenase and 5-lipoxygenase pathway inhibition, anti-proliferative activity, and binding to pharmacologically relevant receptors in the lower urinary tract including alpha-1-adrenoceptors and muscarinic receptors. Meta-analyses of multiple RCTs involving thousands of men show mild-to-moderate improvements in symptom scores and peak urinary flow rate. A 2014 randomized trial of 225 men found that a combination therapy of Saw palmetto with Lycopene, selenium, and tamsulosin was more effective than single therapies in improving International Prostate Symptom Score and increasing maximum urinary flow rate. Clinical studies of up to 320 mg/day for periods up to 10 years have shown the extract to be generally well tolerated with no progression of symptoms. Saw palmetto does not appear to affect readings of prostate-specific antigen (PSA) levels.

Pygeum Africanum Bark Extract — 40.00 mg

Pygeum (Prunus africana) bark extract has been used in European phytomedicine since 1969 for the treatment of mild to moderate symptomatic BPH. The bark of the African plum tree was traditionally used by Zulu people for the discomfort of prostate problems, and European travelers learned of its applications as early as the 1700s. The extract contains three principal bioactive categories: phytosterols (principally β-sitosterol) with anti-inflammatory effects, pentacyclic triterpenes with anti-edema properties, and ferulic acid esters that may indirectly control testosterone activity in the prostate. A 2002 Cochrane review of 18 randomized controlled trials involving 1,562 men found that men using Pygeum were more than twice as likely to report improvement in overall symptoms compared to placebo, with a 23% increase in peak urine flow and 24% reduction in post-void residual volume. The extract has also demonstrated antiproliferative and apoptotic effects on prostate fibroblasts and myofibroblasts in preclinical studies, along with modulation of age-related bladder detrusor hypercontractility. Published clinical data from over 2,200 patients over 25 years show that Pygeum bark extract is generally well tolerated.

Pumpkin Seed Oil — 40.00 mg

Pumpkin seed oil (Cucurbita pepo) is distinguished by its unusual phytosterol profile, rich in Δ7-sterols that may inhibit 5α-reductase activity. It is officially monographed by the German Commission E and ESCOP for irritable bladder symptoms and micturition problems in BPH stages 1 and 2. Multiple clinical trials support its use for prostate and urinary health. A meta-analysis of two randomized, placebo-controlled 12-month trials confirmed that Pumpkin seed extract significantly improved lower urinary tract symptoms and quality of life in men with BPH. A single-blind RCT comparing Pumpkin seed oil to tamsulosin found meaningful symptom relief, and a 24-month noninterventional study confirmed improvements in IPSS and quality of life without negative sexual effects. Pumpkin seed oil also has clinical evidence for supporting bladder health beyond BPH — a 2014 randomized, double-blind, placebo-controlled trial in 120 women with overactive bladder found significant reductions in urinary frequency, urgency, nocturia, and incontinence. The oil is rich in essential fatty acids, Zinc, and phytosterols that collectively support prostate tissue function.

Nettle Root Extract — 75.00 mg

Stinging Nettle root (Urtica dioica) is used in traditional European medicine and has clinical trial support for BPH. The root contains phytosterols, lignans, and polysaccharides implicated in anti-inflammatory and anti-proliferative effects. A systematic review published in 2025 evaluated six RCTs with a total of 1,210 BPH patients and found that Nettle root modestly improved IPSS scores versus controls. A large double-blind, placebo-controlled RCT of 620 patients demonstrated significant improvements in IPSS, and a separate RCT of 558 men showed significant improvements in IPSS, post-void residual volume, and prostate size versus placebo. Proposed mechanisms include inhibition of sex hormone-binding globulin (SHBG) binding on prostate membranes and suppression of aromatase activity. Products containing Nettle root are specifically recommended in European phytotherapy for the symptomatic treatment of urinary disorders including urinary frequency, nocturia, and urinary retention associated with BPH.

Lycopene (from Tomatoes) — 1.00 mg

Lycopene is a bright red carotenoid found primarily in tomatoes, possessing the highest singlet-oxygen quenching ability among dietary carotenoids — exceeding β-carotene by at least twofold. It concentrates in prostate tissue, where research suggests it may reduce oxidative and inflammatory drivers of prostate growth. A pilot RCT of 40 BPH patients receiving 15 mg/day for 6 months found that Lycopene significantly prevented prostate enlargement on ultrasonography, reduced PSA, and improved IPSS more than placebo. The PROCOMB multicenter RCT of 225 men found that Lycopene combined with Saw palmetto and selenium improved IPSS and maximum urinary flow beyond single therapies. Multiple epidemiological studies link higher Lycopene consumption with decreased prostate cancer risk, and laboratory studies show inhibition of prostate cell proliferation and induction of apoptosis. However, clinical trial evidence for cancer prevention remains inconclusive at this time.

Soybean Oil

Soybean oil serves as the lipid base of this softgel formula, helping to preserve the potency of the fat-soluble active ingredients such as Saw palmetto, Pygeum bark extract, and Pumpkin seed oil. Population studies associate higher soy isoflavone consumption with reduced prostate cancer risk. Soy isoflavones may modulate androgen receptor activity and inhibit androgen-dependent gene expression in prostate tissue, though clinical trials have shown inconsistent effects on PSA levels. The oil also provides essential fatty acids including linoleic acid (omega-6) and alpha-linolenic acid (omega-3).

Lecithin

Lecithin is a mixture of phospholipids — including phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol — that serves as a natural emulsifier in this formula. Its amphiphilic properties help facilitate the absorption of lipid-soluble ingredients in the digestive tract, supporting the bioavailability of the fat-soluble botanicals and nutrients in this Prostate Support formula. Phosphatidylcholine, the principal component of Lecithin, is a major component of cell membranes throughout the body and plays an important role in normal cellular metabolism.

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Prostate Support

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Who Benefits

Who Should Consider Prostate Support?

This Prostate Support formula is especially designed for men concerned about prostate health and the urinary symptoms that can accompany prostate changes. It may be particularly relevant for:

Men experiencing lower urinary tract symptoms: Including frequent urination, nocturia (waking at night to urinate), weak urine stream, urgency, and the sensation of incomplete bladder emptying — hallmark symptoms associated with BPH.
Men looking for nutritional support for prostate health: The combination of Zinc, Saw palmetto, Pygeum, Pumpkin seed oil, Nettle root, and Lycopene targets multiple pathways that research suggests are involved in maintaining healthy prostate tissue and function.
Men interested in complementary approaches: Research suggests that combination therapies — such as Saw palmetto with Lycopene and selenium — may offer more consistent benefits than single-ingredient approaches for prostate and urinary concerns.

This product is dairy free and grain free. It is formulated for adult men and is not intended for use by children, women who are pregnant or nursing, or individuals with known allergies to any of the listed ingredients.

Directions

How to Take Prostate Support

Take one (1) softgel capsule, four (4) times daily with meals. Store in a cool, dry place and away from direct light.

Each bottle contains 60 softgels. The serving size is 1 softgel. Taking softgels with meals supports absorption of the fat-soluble ingredients, including Saw palmetto, Pygeum bark extract, Pumpkin seed oil, and Lycopene.

About the author

Written by Greg Howlett

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What symptoms of BPH may Prostate Support help with?

This Prostate Support formula is designed to help reduce symptoms of benign prostatic hyperplasia (BPH), including urinary frequency, nocturia, weak urine stream, urgency, and incomplete bladder emptying. The ingredients — including Saw palmetto, Pygeum, Nettle root, and Pumpkin seed oil — have each been studied in clinical trials for their potential to improve International Prostate Symptom Scores and urinary flow parameters in men with BPH.

Why is this Prostate Support formula in a softgel?

The softgel format is used to preserve the potency of the fat-soluble active ingredients, particularly Saw palmetto and Pygeum bark extracts. These ingredients rely on their lipid-soluble constituents — such as fatty acids and phytosterols — for biological activity. A softgel encapsulation protects these compounds from degradation by light and oxygen, helping to maintain their effectiveness.

What does beta-sitosterol do in this formula?

The formula contains Pygeum africanum standardized to 13% beta-sitosterol. Beta-sitosterol is a phytosterol with anti-inflammatory properties that works by interfering with the formation of prostaglandins that tend to accumulate in the prostate of men with BPH. Phytosterols are also found in Pumpkin seed oil (as Δ7-sterols) and contribute to the formula's overall mechanism of supporting healthy prostate tissue.

How long does it take for Prostate Support ingredients to show benefits?

Clinical studies on the key ingredients in this formula — including Saw palmetto, Pygeum, Nettle root, and Pumpkin seed oil — have used treatment periods ranging from 8 weeks to 12 months. Some studies report initial improvements in urinary symptom scores within 4 to 8 weeks, while peak urinary flow improvements may become statistically significant after 6 to 12 months of consistent use. Individual results may vary.

Does Saw palmetto affect PSA test results?

Research indicates that Saw palmetto does not affect readings of prostate-specific antigen (PSA) levels, even when taken in higher-than-usual amounts. A large clinical study evaluating high doses of Saw palmetto definitively established the lack of an effect on PSA, confirming that clinicians need not adjust serum PSA levels in men taking this herbal supplement who opt to undergo testing for prostate cancer early detection.

Is this Prostate Support formula safe for long-term use?

The individual ingredients in this formula have been studied over extended periods. Saw palmetto has been used safely in research for up to 3 years, and one study followed patients for up to 10 years at 320 mg daily with no reported adverse effects. Pygeum bark extract has published clinical data from over 2,200 patients spanning 25 years, showing it to be well tolerated. As with any supplement, consult your healthcare provider before starting or continuing long-term use, especially if you take prescription medications.

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