
B-Complex Plus

What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| biotin | 400.0 mcg |
| folate (as Metafolin® L-5-MTHF) | 667.0 mcg |
| niacin (as niacinamide and 8% inositol hexaniacinate (no-flush niacin)) | 108.0 mg |
| pantothenic acid ( as calcium pantothenate) (B5) | 100.0 mg |
| riboflavin (as vitamin B2 and 60% riboflavin 5' phosphate (activated B2)) | 12.7 mg |
| thiamin (as thiamin HCI) (B1) | 100.0 mg |
| vitamin B12 (as methylcobalamin) | 400.0 mcg |
| vitamin B6 (as pyridoxine HCI and 40% pyrodoxal 5' phosphate (activated B6)) | 16.7 mg |
| Other ingredients: ascorbyl palmitate, vegetarian capsule (cellulose, water) |
Recommended use
As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.
Days supply
30-60 days
UPC
766298000244
Product categories
Health conditions
Body systems
How it works
This balanced combination of functionally interrelated B vitamins provides wide ranging benefits, including methylation, nerve and energy support.
• Universally supportive, comprehensive B-complex
• Methylated folate (400 mcg)
• Methylated vitamin B12 (400 mcg)
• Energy synthesis
Pure Encapsulations® products are formulated using high-quality, pure ingredients, FREE FROM unnecessary additives and many common allergens including: Wheat, dairy, soy, eggs, artificial sweetners, coatings, GMOs, tree nuts, binders, fillers, magnesium stearate, preservatives, gluten, trans fat and hyfrogenated oils.
Why take this product?
- ✓Helps address mild memory problems associated with normal age-related cognitive decline‡.
- ✓With Metafolin® L-5-MTHF, the predominant, naturally occurring form of folate.
- ✓L-5-MTHF is directly usable by the body because it does not require activation by DHFR (dihydrofolate reductase) and MTHFR (methylene tetrahydrofolate reductase), bypassing these enzymatic steps. L-5-MTHF provides all of the benefits of folic acid, regardless of genetic variations in MTHFR, which affect more than half of the US population.
- ✓Riboflavin enhances MTHFR activity and methylation competence in individuals homozygous for the MTHFR 677T allele‡.
- ✓Riboflavin supports vascular function in MTHFR TT carriers‡.
- ✓Supports cellular energy production and nutrient metabolism‡.
- ✓Promotes healthy methylation, a process that maintains healthy gene expression, neurotransmitter production and homocysteine metabolism. Methylation plays important roles in cardiovascular health, neurocognitive health and emotional wellness‡.
- ✓Supports cardiovascular, neurological and psychological health..
- ✓Promotes cognitive function and positive mood.
- ✓A comprehensive blend of B vitamins in one, easy-to-take supplement.
- ✓Methylated vitamin B12.
- ✓Made with high-quality vegan ingredients backed by verifiable science.

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Book a free consultationFrequently Asked Questions
Everything you need to know about this product.
What is Pure Encapsulations B-Complex Plus?
B-Complex Plus is a comprehensive B vitamin formula that supports energy production, healthy methylation, and nervous system function. It features methylated folate as Metafolin L-5-MTHF (667 mcg) and methylated vitamin B12 as methylcobalamin (400 mcg), along with a full range of B vitamins. It is made with high-quality vegan ingredients and is free from gluten, dairy, soy, GMOs, and many common allergens.
What makes the methylated forms of folate and B12 in this product important?
The L-5-MTHF folate in B-Complex Plus is the predominant, naturally occurring form of folate that your body can use directly, bypassing the enzymatic steps that require DHFR and MTHFR. This is especially helpful because genetic variations in MTHFR affect more than half of the US population. The riboflavin in the formula also enhances MTHFR activity and methylation competence. Healthy methylation supports cardiovascular health, neurotransmitter production, homocysteine metabolism, and cognitive function.
How do I take B-Complex Plus?
Take 1 capsule, 1-2 times daily, with meals. Each bottle contains 60 capsules, providing a 30- to 60-day supply depending on how many capsules you take per day.
Who is B-Complex Plus a good fit for?
It suits adults looking for broad B vitamin support for energy, methylation, nervous system health, and cognitive function. It is vegan and vegetarian friendly. If you are pregnant, breastfeeding, taking medication, or considering this for a child, consult a qualified healthcare practitioner first.
How does B-Complex Plus compare to similar products you carry?
If you need a higher capsule count for longer-term use, PureGenomics B-Complex (120 capsules) or B-Supreme (120 capsules) may be worth considering. If your focus is specifically on B12 and folate rather than a full B-complex, B12 Folate (60 capsules), Ultra B12-Folate (90 capsules), or B12 5,000 Liquid (30 ml) offer more targeted options. B-Complex Plus is a great all-around choice when you want a complete, methylated B vitamin formula in a convenient single-capsule serving.
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