
FidoSpore
What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| Pediococcus acidilactici PA5051 | 4 Billlion CFU |
| Bacillus licheniformis SL-307 | 4 Billion CFU |
| Bacillus subtilis HU58 | 4 Billion CFU |
| Other ingredients: De-fatted grass-fed beef liver extract |
Recommended use
CATS + DOGS: Add 1 capsule to your pet’s food once daily. Capsule can be opened and sprinkled onto food or consumed whole. Dosing is not dependent on weight.
Days supply
30 days
UPC
787790357018
Product categories
How it works
FidoSpore is a once-daily probiotic capsule formulated specifically for dogs and cats, containing a three-strain blend of spore-forming and lactic acid-producing bacteria alongside defatted, grass-fed beef liver for palatability. Each capsule can be given whole or opened and sprinkled onto food, and dosing is not weight-dependent. The formula was developed using the same spore-based probiotic technology found in Microbiome Labs' human products, applied to the unique digestive environment of companion animals. A published 30-day clinical study on the FidoSpore strain blend demonstrated support for digestive health in dogs, providing direct species-specific evidence for the formula.
The three active strains each contribute distinct mechanisms. Bacillus subtilis HU58 and Bacillus licheniformis SL-307 are both spore-forming organisms whose endospore structure allows them to survive the gastric environment and arrive in the intestine intact — a critical advantage for a supplement that must pass through the canine digestive tract, which has a shorter transit time and higher gastric acidity than the human GI system. Once germinated, both strains produce digestive enzymes that assist in food breakdown, generate short-chain fatty acids that fuel colonocytes and support the intestinal barrier, and contribute to immune regulation. Bacillus licheniformis SL-307 additionally produces B vitamins as metabolic byproducts during its active phase in the gut. Pediococcus acidilactici is a lactic acid-producing bacterium with a history of use in veterinary settings for digestive symptoms including constipation and diarrhea, and has been studied in dogs infected with parvovirus for its supportive role in recovery of normal intestinal function.
Canine gut health has meaningful consequences beyond digestive comfort. The dog gut microbiome influences immune function, nutrient absorption, and overall systemic health in ways that parallel what is understood about the human microbiome. Disruptions to the canine microbiome — caused by diet changes, antibiotic use, stress, or illness — can lead to dysbiosis, loose stool, poor coat condition, and immune dysregulation. Spore-based probiotics like those in FidoSpore are particularly well-suited to the canine digestive environment because their stability does not depend on refrigeration and their survivability through gastric acid is not contingent on a fragile live culture. The formula's clinical study, published in the journal Animals, provides the kind of species-specific evidence that is uncommon in the pet supplement category, where most products rely on extrapolation from human data.
Why take this product?
- ✓Clinically studied spore probiotic supports digestive health in dogs.*
- ✓B. subtilis HU58 and B. licheniformis produce digestive enzymes.*
- ✓Pediococcus acidilactici supports dogs with constipation and diarrhea.*
- ✓Defatted grass-fed beef liver added for flavor and palatability.*

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Everything you need to know about this product.
What is FidoSpore?
FidoSpore is a once-daily probiotic capsule from Microbiome Labs formulated specifically for dogs and cats. It contains a three-strain blend of spore-forming and lactic acid-producing bacteria, plus defatted grass-fed beef liver for palatability. The formula is backed by a published 30-day clinical study demonstrating support for digestive health in dogs.
What are the active strains in FidoSpore and what do they do?
Each capsule provides 4 billion CFU each of Bacillus subtilis HU58, Bacillus licheniformis SL-307, and Pediococcus acidilactici PA5051. The two Bacillus strains are spore-forming organisms that survive gastric acid to reach the intestine, where they produce digestive enzymes and short-chain fatty acids that may support the intestinal barrier. Bacillus licheniformis also produces B vitamins as a metabolic byproduct. Pediococcus acidilactici is a lactic acid-producing bacterium that has been used in veterinary settings to support dogs with constipation and diarrhea.
How do I give FidoSpore to my pet?
Add 1 capsule to your pet's food once daily. You can give the capsule whole or open it and sprinkle the contents onto food. Dosing is the same regardless of your pet's weight, making it simple for both cats and dogs.
Who is FidoSpore for?
FidoSpore is designed for dogs and cats whose owners want to support their pet's digestive health with a clinically studied probiotic. It may be especially helpful for pets experiencing microbiome disruptions from diet changes, antibiotic use, stress, or illness. If your pet has a serious health condition, consult your veterinarian before starting any supplement.
How does FidoSpore compare to the other probiotics you carry?
FidoSpore is formulated specifically for dogs and cats, whereas products like Acidophilus, Probiotic Blend, Vidophilus 35 Billion, and Ultra Dairy Support are designed for human use. Its spore-based strains are chosen for their ability to survive the higher gastric acidity and shorter transit time of the canine digestive tract. If you are looking for a probiotic for yourself rather than your pet, one of those human-oriented options would be a better fit.
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