
Folate 5,000 Plus

What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| vitamin B6 (as pyridoxal 5' phosphate (activated B6)) | 25.0 mg |
| folate (as metafolin, L-5-MTHF) | 8,333 (5,000) mcg DFE (mcg L-5-MTHF) |
| vitamin B12 | 1000.0 mcg |
| Other ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water) |
Recommended use
As a dietary supplement, take 1 capsule daily, with a meal or as directed by a health professional.
Days supply
60 days
UPC
766298017884
Product categories
Health conditions
How it works
Folate 5,000 Plus is a premium dietary supplement designed to deliver 5,000 mcg of folate in its biologically active form, methyltetrahydrofolate (5-MTHF). Unlike traditional folic acid, 5-MTHF is universally metabolized and bypasses common genetic variations, such as those involving the MTHFR enzyme, ensuring it is readily usable by the body. This innovative formulation also includes activated forms of vitamin B12 (methylcobalamin) and vitamin B6 (pyridoxal-5-phosphate), enhancing the synergistic benefits of B vitamins for optimal health and wellness.
This advanced supplement plays a crucial role in promoting healthy methylation, a fundamental biochemical process that regulates genetic expression and supports numerous cellular functions. Healthy methylation is essential for maintaining hormone balance, neurotransmitter production, energy metabolism, and overall cellular health. Folate, in its active form, provides methyl groups that are critical for these processes, ensuring that your body operates at its best, even in the presence of genetic variations that may impair the metabolism of standard folic acid.
Folate 5,000 Plus supports the production of healthy DNA, fostering cellular regeneration and repair. Research also highlights its role in maintaining a healthy nervous system, with studies showing that the combination of methylfolate, methylcobalamin, and pyridoxal-5-phosphate promotes nerve health and comfort. Additionally, the active B vitamins in this formula are known to contribute to psychological well-being, supporting a positive mood and mental clarity.
Ideal for individuals seeking a highly bioavailable and effective form of folate, Folate 5,000 Plus is particularly beneficial for those with genetic variations affecting folate metabolism. Whether you’re looking to optimize your energy levels, support your nervous system, or promote healthy methylation, this scientifically backed formula delivers targeted benefits to help you thrive.
Why take this product?
- ✓Delivers the active form of folate for immediate bioavailability, requiring no metabolic activation.
- ✓Supports optimal cellular and neuronal health.
- ✓Enhances neurotransmitter function and promotes a positive mood.
- ✓Provides 5,000 mcg of activated folate in every capsule.
- ✓Features a synergistic blend of activated B vitamins.
- ✓Crafted with premium, vegan ingredients and grounded in proven science.

Ask her about supplements, interactions, or what you actually need. A free 15-minute call, or send her an email.
Book a free consultationFrequently Asked Questions
Everything you need to know about this product.
What is Folate 5,000 Plus by Pure Encapsulations?
Folate 5,000 Plus is a dietary supplement that provides 5,000 mcg of folate in its biologically active form, L-5-MTHF (Metafolin). It also includes activated vitamin B12 (methylcobalamin) at 1,000 mcg and activated vitamin B6 (pyridoxal 5' phosphate) at 25 mg. This synergistic blend of B vitamins is designed to support healthy methylation, cellular health, and nervous system function.
What do the active ingredients in Folate 5,000 Plus do?
The L-5-MTHF folate bypasses common genetic variations like those involving the MTHFR enzyme, so your body can use it right away without metabolic conversion. Activated B12 and B6 work alongside folate to promote healthy methylation, which supports DNA production, neurotransmitter balance, energy metabolism, and a positive mood. Together, these three B vitamins also promote nerve health and comfort.
How do I take Folate 5,000 Plus?
Take 1 capsule daily with a meal, or as directed by a health professional. Each bottle contains 60 capsules, providing a 60-day supply.
Who is Folate 5,000 Plus best suited for?
It is particularly beneficial for individuals with genetic variations that affect folate metabolism, since the active L-5-MTHF form requires no conversion. It may also suit anyone looking to support energy, nervous system health, neurotransmitter balance, or healthy methylation. The formula is both vegan and vegetarian. If you are pregnant, breastfeeding, taking medication, or considering this for a child, consult a qualified healthcare practitioner first.
How does Folate 5,000 Plus compare to similar Pure Encapsulations products?
Folate 5,000 Plus delivers a high-potency 5,000 mcg dose of activated folate, making it a more targeted option than products like B12 Folate (60 capsules) or B-Complex Plus (60 capsules), which provide broader B-vitamin support at lower folate levels. If you need comprehensive B-complex coverage, PureGenomics B-Complex (120 capsules) or B-Complex 100 mg Sustained Release (100 tablets) may be worth considering. For those focused specifically on homocysteine support, Homocysteine Supreme (120 capsules) is another option in the range.
What people are saying
Be the first to review this product
Best Sellers

PhytoMultiâ„¢ Multivitamin

ArthroSootheâ„¢

Zinc Picolinate 30 mg
