
Mega IgG2000
What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| Serum-derived immunoglobulin concentrate (Immunolin®) (providing 900 mg Immunoglobulin G [IgG]) | 2 g |
Recommended use
Ages 2+ Take 1 scoop daily with or without food, or as directed by your healthcare practitioner. Mix powder into 16 oz of cold water or liquid of your choice. Stir for 20 seconds. Children under the age of 2, please consult your healthcare practitioner. Drink plenty of fluids.
Days supply
30 days
UPC
ML-MIGGP
Product categories
How it works
Mega IgG2000 Powder is a serum-derived bovine immunoglobulin concentrate providing 2 grams of ImmunoLin® per one-scoop daily serving, mixed into 16 ounces of water or a beverage of choice. It delivers the same immunoglobulin formula as the Mega IgG2000 capsules in a powder format that may be preferable for children, individuals who have difficulty swallowing capsules, or those who want to mix it into a smoothie or functional beverage. It is appropriate for adults and children ages 2 and older who want to support intestinal barrier integrity, mucosal immune function, and healthy digestion without exposure to dairy proteins. The formula is not appropriate for individuals with a beef allergy.
The sourcing of the immunoglobulins is the formula's primary differentiator from colostrum and whey-based IgG products on the market. ImmunoLin® is derived from bovine serum — blood-based rather than milk-based — which eliminates lactose, casein, and β-lactoglobulin, making it a viable option for individuals who are intolerant or sensitive to dairy proteins but still require the gut barrier and immune support that oral immunoglobulins provide. Serum-derived sources also tend to deliver a higher immunoglobulin concentration per gram than colostrum-based products. Each serving provides approximately 900–1,012 mg of IgG, 92–100 mg of IgM, and 18–20 mg of IgA, alongside 100 mg of bovine serum albumin. IgG binds a broad range of bacterial, viral, and fungal antigens in the gut lumen; IgM provides a broader first-line luminal immune response; and IgA functions as the primary secretory immunoglobulin at mucosal surfaces, where it is naturally produced to coat and protect the intestinal epithelium.
When consumed, the immunoglobulins in Mega IgG2000 transit through the gastrointestinal lumen where they bind to luminal antigens — including lipopolysaccharides (LPS), flagellin, mycotoxins, and other inflammatory triggers — and facilitate their clearance from the gut before translocation across the mucosal barrier can occur. Research on serum-derived bovine immunoglobulin (SBI) demonstrates that it binds conserved microbial antigens associated with immune activation, reduces gut permeability, and supports gut homeostasis without disrupting commensal or probiotic bacteria. An ex vivo study found that SBI at equivalent doses significantly increased production of the short-chain fatty acids acetate, propionate, and butyrate — compounds that fuel colonocytes and support mucosal repair. The ImmunoLin® ingredient has been studied in over 10 published human clinical trials across a range of gastrointestinal conditions, including a randomized, double-blind, placebo-controlled study in children with IBS-D that found improvements in stool frequency, quality of life scores, and functional disability compared to placebo.
Why take this product?
- ✓Dairy-free immunoglobulin concentrate supports gut barrier function.*
- ✓2g ImmunoLin® delivers IgG, IgM, and IgA per serving.*
- ✓Serum-derived source is lactose-free, casein-free, and β-lactoglobulin-free.*

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Everything you need to know about this product.
What is Mega IgG2000 Powder?
Mega IgG2000 Powder from Microbiome Labs is a dairy-free, serum-derived bovine immunoglobulin concentrate in a convenient powder format. Each one-scoop serving delivers 2 grams of ImmunoLin®, providing immunoglobulins IgG, IgM, and IgA that support intestinal barrier integrity, mucosal immune function, and healthy digestion.
What are the key ingredients and how do they work?
The active ingredient is 2 g of ImmunoLin®, a serum-derived immunoglobulin concentrate providing approximately 900 mg of IgG along with IgM and IgA. These immunoglobulins travel through the gut lumen where they bind to inflammatory triggers such as lipopolysaccharides, flagellin, and mycotoxins, helping facilitate their clearance before they can cross the mucosal barrier. Because ImmunoLin® is sourced from bovine serum rather than milk, it is free of lactose, casein, and β-lactoglobulin, making it a viable option for people sensitive to dairy proteins.
How do I take Mega IgG2000 Powder?
Take 1 scoop daily with or without food, or as directed by your healthcare practitioner. Mix the powder into 16 oz of cold water or the liquid of your choice and stir for 20 seconds. Be sure to drink plenty of fluids throughout the day. For children under the age of 2, consult your healthcare practitioner before use.
Who is Mega IgG2000 Powder best suited for?
It is appropriate for adults and children ages 2 and older who want to support gut barrier function and mucosal immunity without exposure to dairy proteins. The powder format may be especially helpful for children, individuals who have difficulty swallowing capsules, or anyone who prefers to mix it into a smoothie or beverage. It is not appropriate for individuals with a beef allergy. If you are pregnant, breastfeeding, or taking medication, consult a qualified healthcare practitioner before use.
How does Mega IgG2000 compare to other products in this category?
Unlike traditional probiotic capsules and tablets such as Acidophilus, Probiotic Blend, and Vidophilus 35 Billion, Mega IgG2000 is not a probiotic — it is a concentrated immunoglobulin formula designed to bind and clear antigens in the gut lumen and support barrier integrity. It also differs from broad nutritional formulas like Life's Essentials Plus because its focus is specifically on mucosal immune support. For those with dairy sensitivities, Mega IgG2000 offers a dairy-free alternative to colostrum or whey-based immunoglobulin products, unlike Ultra Dairy Support which is oriented toward dairy digestion.
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