
SAM-e

What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| s-adenosylmethionine | 400 mg |
| Other ingredients: calcium oxide coating (talc, flake shellac dewaxed, arginine base, glycerol, magnesium stearate, collodial silica anhydrous, sodium alginate), colloidal silica anhydrous, disulfate p-toluensulronate, magnesium hydroxide, magnesium stearate, microcrystalline cellulose, s-adenosyl-l-methionine disulfate p-toluensulronate, stearic acid |
Recommended use
Take 2 tablets daily.
Days supply
15 days
UPC
099904018457
Product categories
Health conditions
Body systems
Expiration date
08/2027
How it works
Nature's Sunshine SAM-e supports emotional health, boosts energy levels, nourishes the liver, and promotes a healthy structural system. S-Adenosyl-methionine tosylate, or SAM-e, occurs naturally in all living cells and assists in biochemical reactions that are essential to bodily functions, specifically the production of neurotransmitters and the continual repair of cartilage. Nature's Sunshine SAM-e contains 200 mg of SAM-e.
STOCK NUMBER: 1845-2
Why take this product?
- ✓Balances mood
- ✓Nourishes joints
- ✓Promotes regeneration of new cells
- ✓Encourages muscle and nerve health
- ✓Nourishes the liver

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Book a free consultationFrequently Asked Questions
Everything you need to know about this product.
What is Nature's Sunshine SAM-e?
Nature's Sunshine SAM-e provides S-adenosyl-L-methionine, a compound that occurs naturally in all living cells and plays a vital role in essential biochemical reactions throughout the body. Each serving delivers 400 mg of SAM-e to support mood balance, joint health, energy levels, liver function, and the nervous system.
What does SAM-e do in the body?
SAM-e assists in the production of neurotransmitters, which are key to emotional well-being and nervous system function. It also supports the continual repair of cartilage and promotes the regeneration of new cells, making it beneficial for both joint health and overall vitality.
How do I take Nature's Sunshine SAM-e?
Take 2 tablets daily. Each bottle contains 30 tablets, providing a 15-day supply at the recommended serving.
Who might benefit from taking SAM-e?
SAM-e is well-suited for adults looking to support their mood, nourish their joints and liver, or promote muscle and nerve health. Anyone who is pregnant, nursing, or taking prescription medication should consult their healthcare provider before use.
How does SAM-e compare to other mood and emotional support products?
SAM-e takes a unique approach by supplying a naturally occurring compound involved in neurotransmitter production and cartilage repair, making it a good fit if you want both mood and joint support in one product. Mood Elevator TCM and AnxiousLess focus more specifically on emotional balance through herbal formulas, while Methyl Combo and Liquid Methyl Vitamin B-12 Complete center on methylation and B-vitamin support. INSPIRE Uplifting Blend offers aromatic support as an essential oil. Your choice depends on whether you're looking for broad structural and emotional support or a more targeted approach.
What people are saying
- Deserae9/15/2025Great for stress
I take 2 each morning, it’s really helped with stress management. I will make sure I'm not going without!
- Nancy9/15/2025
SAM-e
- Analese Lawn9/15/2025Great!
I’ve been taking sam-e for a month and can already feel a difference
- Debra Cupani9/15/2025Bad experience
This product did not work well for me. It not only gave me dry mouth but one night, while trying to sleep, I experienced too many disconnected thoughts that I was not thinking about. Will not buy again.
- Becky Smith9/15/2025
Great product, great company!
- Steamer9/15/2025Great
Noticeable difference when taking it.
- Lorene Olson9/15/2025Responsive
High quality products and very responsive to questions or concerns.
- Linda White9/15/2025Same works for me for depression and keeping my mind sharp...
I take two Sames each day....once in the morning and once in the evening. I can tell the difference if I don't take it. I definitely feel a bit low if I don't take it.
- Misty Rattigan9/15/2025
SAM-e
- Elizabeth Evans9/15/2025
SAM-e
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