SAMe
What's inside
Supplement Facts
| Ingredients | Amount |
|---|---|
| vitamin B-6 (as pyridoxal-5-phosphate) | 5.0 mg |
| folate (as Quatrefolic [6S]-5-methyltetrahydrofolate, glucosamine salt 200mcg) | 170.0 mcg |
| vitamin B-12 (as methylcobalamin) | 50.0 mcg |
| SAMe (as s-adenosyl-l-methionine disulfate p-toluensulfate) | 200.0 mg |
| Other ingredients: cellulose (capsule), microcrystalline cellulose, vegetable stearate, calcium chloride anhydrous, calcium oxide |
Recommended use
Take 1 capsule per day, preferably on an empty stomach, or as directed by your health-care practitioner.
Days supply
90 days
UPC
879452003774
Product categories
Health conditions
Body systems
How it works
S-adenosyl-L-methionine (SAMe) is a vital compound naturally produced by the human body that plays a crucial role in numerous biochemical processes essential for health and well-being. This metabolite, synthesized from the amino acid methionine in the presence of vitamin B12 and folate, is renowned for being one of the most active methyl donors in the body. Its importance is often compared to that of adenosine triphosphate (ATP), emphasizing its critical role in maintaining optimal bodily functions. SAMe supports the synthesis of neurotransmitters, phospholipids, melatonin, and polyamines, which are integral to cellular growth and repair.
One of SAMe’s most essential functions is its involvement in DNA methylation, a process that regulates gene expression and ensures the integrity of genetic material. By acting as a source of methyl groups in the nucleus, SAMe helps mask genetic damage and supports healthy cellular activity. Its influence on neurotransmitter production also means it plays a significant role in mood regulation, cognitive health, and emotional balance. SAMe contributes to the synthesis of serotonin, dopamine, and norepinephrine, making it a powerful ally for maintaining a positive outlook and mental clarity.
For those seeking to optimize their physical and mental health, supplementing with SAMe can provide the necessary support for these vital processes. Factors such as stress, poor diet, or genetic variations can impact the body’s natural production of SAMe, making supplementation an effective way to bridge this gap. SAMe is also a key player in liver health and joint function, offering benefits for those dealing with joint discomfort or looking to support detoxification pathways.
By incorporating SAMe into your daily routine, you are giving your body the tools it needs to support cellular health, DNA integrity, and neurotransmitter balance. Whether you’re looking to enhance mood, improve joint mobility, or optimize overall well-being, SAMe is an indispensable part of a healthy lifestyle.
Why take this product?
- ✓Supports cognitive function and memory.
- ✓Promotes a positive mental outlook and emotional balance.
- ✓Contributes to optimal liver health.
- ✓Enhances antioxidant protection.
- ✓May help reduce oxidative damage.
- ✓Supports a healthy inflammatory response.
- ✓Helps maintain cell membrane integrity and flexibility.
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Everything you need to know about this product.
What is Designs for Health SAMe?
Designs for Health SAMe is a vegan-friendly supplement built around S-adenosyl-L-methionine, a naturally occurring compound your body uses as one of its most active methyl donors. Each capsule delivers 200 mg of SAMe alongside supportive B vitamins — pyridoxal-5-phosphate (B-6), methylcobalamin (B-12), and Quatrefolic methylfolate — to promote healthy methylation, neurotransmitter balance, and cellular function. It comes in a 90-capsule bottle for a full 90-day supply.
What do the key ingredients do?
SAMe supports the synthesis of neurotransmitters like serotonin, dopamine, and norepinephrine, and plays a role in DNA methylation and cell membrane integrity. The included methylfolate and methylcobalamin are active forms of folate and B-12 that your body needs to produce and recycle SAMe naturally. Pyridoxal-5-phosphate (active B-6) rounds out the formula by further supporting healthy methylation pathways. Together, these ingredients promote cognitive function, a positive mental outlook, liver health, and a healthy inflammatory response.
How do I take Designs for Health SAMe?
Take 1 capsule per day, preferably on an empty stomach, or as directed by your healthcare practitioner. At this serving size the bottle provides a 90-day supply.
Who is this product for?
It is a good fit for adults looking to support mood, cognitive function, joint comfort, liver health, or overall methylation. The formula is suitable for both vegans and vegetarians. If you are pregnant, breastfeeding, taking medication, or considering this for a child, please consult a qualified healthcare practitioner before use.
How does Designs for Health SAMe compare to similar products in the range?
While products like Homocysteine Supremeâ„¢, B-Supreme, and Liposomal B Supreme focus primarily on B-vitamin support and methylation cofactors, SAMe provides the methyl donor itself along with key B vitamins in one capsule. NeuroRenewâ„¢ is geared toward nervous system support, and Lithium Synergy targets a different aspect of brain health. If your main goal is direct SAMe supplementation for mood, joints, or liver function, this formula is the most targeted option of the group.
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