Hi there. Ive recently started taking some evening primrose oil pills to help with a skin condition. I was just wondering, is there any chance these could be reacting with my PCOS pill.

I do not foresee any potential interactions between the Evening Primrose Oil and your Metformin.  There is nothing in the literature to suggest that this is a possibility.  In fact, Evening Primrose Oil is something I commonly prescribe for women with PCOS.  It is known to naturally help improve the balance between progesterone and estrogen.