Prenatal Pro Designs for Health | Complete Guide

Name: Prenatal Pro™
Brand: Designs For Health
SKU: DH-PRE120
Price: 55.49 USD
Availability: InStock

Discover Prenatal Pro™ by Designs for Health — a methylated prenatal multivitamin with chelated minerals, L-methylfolate, and key nutrients for mom and baby.

Overview

Prenatal Pro Designs for Health: A Comprehensive Prenatal Multivitamin

Prenatal Pro™ is a 4-capsule-per-day multivitamin and multimineral formula designed to provide mom and baby with a broad foundation of key nutrients. Specifically formulated for pregnant and lactating women — and women wishing to become pregnant — Prenatal Pro™ features the bioidentical form of folate and B vitamins alongside chelated minerals for superior nutrient absorption and bioavailability.

The nutrients found in this formula complement an average diet to support a healthy pregnancy and optimal fetal development.* Unlike many prenatals that contain synthetic folic acid, Prenatal Pro™ uses L-methylfolate (as Quatrefolic [6S]-5-methyltetrahydrofolate, glucosamine salt), the bioactive form of folate naturally found in the body.

This prenatal pro designs for health formula is vegetarian, non-GMO, gluten-free, dairy-free, and soy-free — making it accessible for women with common dietary sensitivities.

Key Differentiators

Why Methylfolate, Chelated Minerals, and Bioavailable B Vitamins Matter

Methyl Folate, Not Folic Acid: While methylfolate is important for your baby's brain, many prenatals contain a synthetic format called folic acid. Prenatal Pro™ uses the bioactive form (L-methylfolate) to help ensure you receive the active form naturally found in your body.* This is especially relevant for women with MTHFR gene variants who may have reduced ability to convert folic acid into its usable form.

Chelated Minerals Including Non-Constipating Iron: Iron in this formula is provided as Ferrochel® ferrous bisglycinate chelate — a chelated, non-constipating form. Select minerals including Zinc, Magnesium, and Selenium are also in chelated form, which research suggests may offer superior absorption and bioavailability.*

Bioactive B Vitamins: B vitamins in Prenatal Pro™ are provided in their active coenzyme forms, including pyridoxal-5-phosphate (B6), methylcobalamin (B12), and riboflavin-5-phosphate (B2). These forms bypass certain conversion steps that some individuals may perform inefficiently.

What's inside

Key ingredients

Folate (as Quatrefolic [6S]-5-methyltetrahydrofolate, glucosamine salt) — 1360 mcg

The biologically active, circulating form of vitamin B9, L-methylfolate bypasses the enzymatic conversion step impaired in individuals with MTHFR gene polymorphisms. Clinical trials show it effectively raises serum folate levels. EU and several national health authorities have approved 5-MTHF as a bioequivalent alternative to folic acid for neural tube defect risk reduction during pregnancy. Folate is critical for DNA synthesis, cell division, and neural tube formation during the earliest weeks of fetal development.

Iron (as Ferrochel ferrous bisglycinate chelate) — 27 mg

Iron requirements nearly double during pregnancy to support expanded blood volume, placental development, and fetal Iron stores. Research confirms Iron supplementation may help prevent Iron-deficiency anemia, the most common cause of anemia in pregnancy, which is linked to preterm birth, low birthweight, and impaired infant cognitive development. WHO, ACOG, and NIH ODS all recommend routine Iron supplementation during pregnancy. The bisglycinate chelate form is specifically selected for its non-constipating properties.

Vitamin D (as cholecalciferol) — 25 mcg

Vitamin D is among the most studied prenatal micronutrients, essential for Calcium absorption, fetal skeletal development, immune function, and fetal brain development. Observational and RCT evidence links deficiency to gestational diabetes, preeclampsia, preterm birth, and neurodevelopmental concerns in offspring. Vitamin D insufficiency affects up to 47.9% of individuals globally, with especially high rates in pregnant women. WHO, ACOG, and NICE all provide recommendations for prenatal supplementation.

Vitamin A (as mixed carotenoids and palmitate) — 1500 mcg

Vitamin A is essential for fetal organogenesis, immune function, and vision development. Blood levels may decline during pregnancy without supplementation. WHO recommends Vitamin A supplementation in deficiency-prone areas to reduce maternal night blindness and infant mortality. NIH ODS lists Vitamin A among nutrients with critical prenatal roles. Prenatal formulations carefully stay below the teratogenic upper intake level of 3,000 mcg RAE/day for preformed Vitamin A.

Vitamin C (as ascorbic acid) — 400 mg

Vitamin C is listed by NIH ODS and ACOG among nutrients with critical roles during pregnancy. Blood levels may decline during pregnancy without supplementation. Vitamin C substantially enhances non-heme Iron absorption — clinically important for supporting healthy Iron status in pregnancy. Small intervention studies suggest it may support membrane integrity and urinary tract health during pregnancy.

Vitamin E isomers (as DeltaGold delta and gamma tocotrienols) — 15 mg

Vitamin E is a fat-soluble antioxidant whose blood levels may decline during pregnancy without supplementation. A Mendelian randomization study (2024) found genetically predicted higher Vitamin E levels were inversely associated with spontaneous abortion risk. Vitamin E supports cell membrane protection from oxidative damage and immune function during the critical periods of fetal development.

Vitamin K (as vitamin K1 phytonadione) — 120 mcg

Vitamin K plays critical roles in fetal bone development and coagulation factor synthesis. Blood levels may decline during pregnancy without supplementation. Neonates are routinely given Vitamin K at birth to prevent hemorrhagic disease, and maternal Vitamin K status during pregnancy may affect neonatal coagulation and bone development. It is included in evidence-based prenatal supplement reviews and expert consensus recommendations.

Thiamin (vitamin B-1) (as thiamin HCl) — 1.4 mg

Thiamine is essential for carbohydrate metabolism and neural development, with blood levels declining during pregnancy. An international expert Delphi consensus panel listed thiamine among micronutrients important during pregnancy. Deficiency in pregnancy can cause Wernicke's encephalopathy and is associated with fetal cardiac and neurological concerns. It is especially critical in women with hyperemesis gravidarum.

Riboflavin (vitamin B-2) (as riboflavin-5-phosphate) — 1.6 mg

Provided in its active coenzyme form (FMN), riboflavin-5-phosphate supports mitochondrial energy production, antioxidant defense, and the functional activation of other B vitamins including folate. Riboflavin requirements increase during pregnancy and lactation. FMN is the principal form in which riboflavin is found in cells and is essential for numerous oxidoreductase enzymes.

Niacin (vitamin B-3) (as niacinamide) — 18 mg

Niacinamide (nicotinamide) is the amide form of niacin B3 most commonly used in prenatal vitamins due to its absence of vasodilatory flushing. As an NAD+ precursor, it is critical for fetal DNA repair and energy metabolism during organogenesis. A landmark 2018 NEJM study found maternal NAD+ deficiency from niacin/nicotinamide deficiency causes congenital malformations in animal models; niacinamide rescued this phenotype.

Vitamin B-6 (as pyridoxal-5-phosphate) — 2 mg

Vitamin B6 has established evidence for reducing nausea severity in early pregnancy and is recommended by ACOG as a first-line option for pregnancy nausea and vomiting. NIH ODS and WHO both recognize its role in pregnancy. A Cochrane review supports its use for nausea management. Provided here as pyridoxal-5-phosphate, the metabolically active coenzyme form.

Vitamin B-12 (as Methylcobalamin [MecobalActive]) — 2.8 mcg

Vitamin B12 is critical during pregnancy for hematopoiesis, myelination, and DNA methylation. Research links deficiency to neural tube defects, preeclampsia, low birthweight, and cognitive deficits in offspring. A systematic review of 7 RCTs found beneficial effects of B12 supplementation on offspring neurocognitive development. NIH ODS and ACOG list Vitamin B12 as a critical prenatal nutrient, especially important for vegetarian and vegan pregnant women. Methylcobalamin is a metabolically active form.

Biotin (as d-biotin) — 35 mcg

Biotin levels decrease substantially during pregnancy; approximately half of US pregnant women show biomarkers of mild biotin deficiency. Animal studies demonstrate biotin deficiency during pregnancy may cause facial and limb malformations and impaired fetal development. An evidence-based prenatal supplement review (2022) recommended approximately 100 mcg/day biotin supplementation during pregnancy.

Pantothenic acid (as D-Calcium pantothenate) — 7 mg

Vitamin B5 is a component of coenzyme A essential for fatty acid synthesis and energy metabolism. Blood levels may decline during pregnancy without supplementation. An evidence-based review of prenatal supplements identified pantothenic acid among vitamins that decline during pregnancy, and the adequate intake increases to 6 mg/day during pregnancy.

Choline (as Choline dihydrogen citrate) — 50 mg

Choline is recognized as an essential nutrient critical for fetal neural tube formation, brain development, and placental function. ACOG specifically recommends Choline supplementation during pregnancy. Over 90–95% of US pregnant women fail to meet the adequate intake of 450 mg/day. Lower circulating Choline is associated with increased neural tube defect risk, and prenatal Choline supports fetal neurodevelopment in systematic reviews.

Calcium (as DimaCal di-Calcium malate) — 140 mg

Calcium is critical for fetal skeletal development and is recommended by WHO, ACOG, and multiple professional societies for pregnant women with low dietary intake to support healthy blood pressure. About 21.2% of US pregnant women have dietary Calcium intakes below the estimated average requirement. NIH ODS specifically lists Calcium among critical prenatal nutrients.

Magnesium (as di-Magnesium malate) — 80 mg

Magnesium is an essential mineral for muscle relaxation, bone development, and blood pressure regulation during pregnancy, with levels declining if unsupplemented. Inadequate Magnesium intake is linked to gestational diabetes, preeclampsia, preterm birth, and low birthweight in observational studies. A Cochrane review found Magnesium supplementation was associated with significant reduction in low birthweight risk. NIH ODS lists Magnesium among critical prenatal nutrients underconsumed by pregnant women.

Zinc (as Zinc bisglycinate chelate) — 13 mg

Zinc is critical for cell division, immune function, and fetal growth. Research links deficiency to intrauterine growth restriction, preterm birth, and congenital malformations. NIH ODS lists Zinc among nutrients with critical prenatal roles that are underconsumed. A Cochrane systematic review of Zinc supplementation in pregnancy found significant reductions in preterm birth. The RDA increases to 11 mg/day during pregnancy.

Iodine (as Potassium iodide) — 200 mcg

Iodine is essential for thyroid hormone synthesis, which regulates fetal brain development. The body needs Potassium iodide to provide bioavailable iodine for thyroid function. Adequate iodine during pregnancy supports normal neurodevelopment and prevents cretinism.

Selenium (as Selenium glycinate complex) — 200 mcg

Selenium is an essential trace mineral with critical roles in antioxidant defense via glutathione peroxidases, thyroid hormone metabolism, and immune function. Blood Selenium levels may decline during pregnancy without supplementation. Poor Selenium status is associated with miscarriage, preeclampsia, preterm delivery, and gestational diabetes. Evidence-based prenatal supplement recommendations specifically include Selenium supplementation during pregnancy.

Copper (as TRAACS Copper glycinate chelate) — 1.3 mg

Copper is an essential nutrient during pregnancy, required for fetal brain, heart, vascular, skeletal, and immune development. Maternal Copper requirements increase during gestation. Low maternal serum Copper has been associated with premature delivery and impaired fetal growth indices in observational data. Copper deficiency during embryogenesis may cause structural and biochemical abnormalities.

Manganese (as TRAACS Manganese Bisglycinate Chelate) — 2.6 mg

Manganese is essential for skeletal development through glycosyltransferase-mediated proteoglycan synthesis, collagen formation, and bone mineralization. It also serves as a cofactor for Manganese superoxide dismutase (MnSOD), supporting antioxidant defense. Deficiency in animals causes skeletal abnormalities, reproductive failure, and impaired growth.

Chromium (as TRAACS Chromium nicotinate glycinate chelate) — 45 mcg

Chromium is a trace element involved in macronutrient metabolism and insulin signaling. It is generally believed to support the action of insulin, a hormone critical to the metabolism and storage of carbohydrate, fat, and protein in the body. Needs increase slightly during pregnancy and lactation.

Molybdenum (as TRAACS Molybdenum Glycinate Chelate) — 50 mcg

Molybdenum is an essential trace element required as a cofactor for sulfite oxidase, xanthine oxidase, and aldehyde oxidase — enzymes involved in sulfur amino acid metabolism and purine catabolism. It supports normal metabolic function during pregnancy.

Sunflower Lecithin

Sunflower Lecithin is a phospholipid mixture that supports nutrient absorption and serves as a source of phosphatidylcholine, a structural component of cell membranes. Derived from sunflower rather than soy, it is appropriate for women avoiding soy-based ingredients. Phosphatidylcholine is also a dietary source of Choline, which supports fetal brain development.

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Prenatal Pro™

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Who It's For

Who Should Consider Prenatal Pro™

Prenatal Pro™ was specifically formulated for three groups of women:

Women wishing to become pregnant: Research suggests the earlier that supplementation begins, the better. Adequate vitamin stores help support a growing baby's nutrient needs from the very start of pregnancy.
Pregnant women in any trimester: The methylated prenatal vitamins in this formula can be used throughout all stages of pregnancy to complement an average diet.
Breastfeeding mothers: Prenatal Pro™ can also be used as postnatal vitamins for breastfeeding moms, supporting nutritional demands during lactation.*

Women with MTHFR gene polymorphisms may find this formula especially well-suited, as the methylfolate form bypasses the enzymatic conversion step that is impaired by common MTHFR variants.

How to Take

Directions for Use

Take 4 capsules per day with meals or as directed by your health-care practitioner.

Each bottle contains 120 capsules, providing a 30-day supply at the recommended serving size of 4 capsules daily.

About the author

Written by Greg Howlett

Greg Howlett

Founder

Greg has spent over a decade helping customers choose the right natural-health products. He personally vets every formula we carry and writes these guides to cut through the marketing noise with practical, experience-based advice.

FAQ

Frequently asked questions

What makes Prenatal Pro™ different from other prenatal vitamins?

Prenatal Pro™ uses L-methylfolate (as Quatrefolic) instead of synthetic folic acid, ensuring you receive the bioactive form of folate naturally found in your body. It also features chelated minerals — including non-constipating Iron as Ferrochel ferrous bisglycinate chelate — and bioactive B vitamins like pyridoxal-5-phosphate (B6) and methylcobalamin (B12) for superior absorption and bioavailability.*

Can I take Prenatal Pro™ before I become pregnant?

Yes. Prenatal Pro™ was specifically formulated for women wishing to become pregnant, in addition to pregnant and lactating women. Research suggests that the earlier supplementation begins, the better, as adequate vitamin stores help support a growing baby's nutrient needs from conception.

Is this prenatal suitable for women with MTHFR gene variants?

Prenatal Pro™ uses L-methylfolate rather than folic acid. The methylfolate form bypasses the enzymatic conversion step that is impaired in individuals with MTHFR gene polymorphisms, making it especially relevant for women with these common genetic variants.

Will the Iron in this formula cause constipation?

Prenatal Pro™ contains Iron as Ferrochel ferrous bisglycinate chelate, a chelated, non-constipating form. This chelated Iron is designed to offer superior absorption while minimizing the gastrointestinal discomfort commonly associated with conventional Iron supplements.*

Is Prenatal Pro™ suitable for women with dietary restrictions?

Yes. Prenatal Pro™ is vegetarian, non-GMO, gluten-free, dairy-free, and soy-free. The Lecithin in the formula is derived from sunflower rather than soy, making it appropriate for women avoiding soy-based ingredients.

Can I continue taking Prenatal Pro™ after delivery while breastfeeding?

Yes. Prenatal Pro™ can be used as postnatal vitamins for breastfeeding moms. Nutrients like thiamine, Vitamin B12, and Choline are especially important during lactation, as maternal status directly influences breast milk nutrient content and infant nutritional intake.*

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