Iron (Iron (Fe))
Synopsis of iron
Iron is an essential trace mineral required for a wide range of physiological functions, most importantly the production of hemoglobin in red blood cells and myoglobin in muscle tissue, both of which are critical for oxygen transport and storage. Iron also plays a vital role in energy metabolism, DNA synthesis, immune function, and enzymatic activity.
The body tightly regulates iron levels, absorbing more when stores are low and less when adequate. Dietary iron comes in two forms:
- Heme iron, found in animal products like red meat, poultry, and fish—more efficiently absorbed
- Non-heme iron, found in plant sources like spinach, lentils, tofu, and fortified grains—less bioavailable but enhanced by vitamin C intake
Iron deficiency is one of the most common nutrient deficiencies globally and can lead to iron-deficiency anemia, characterized by fatigue, weakness, pale skin, shortness of breath, cold intolerance, and poor cognitive function. It is especially common in menstruating women, pregnant individuals, infants, vegetarians, and people with malabsorption or chronic blood loss.
Iron is often supplemented in the form of ferrous sulfate, ferrous gluconate, ferrous fumarate, or newer chelated forms (like iron bisglycinate) that offer improved absorption and reduced gastrointestinal side effects.
Historical Use
Iron has been used medicinally for thousands of years. Ancient civilizations such as the Greeks, Romans, and Egyptians used rust (iron oxide) mixed with wine or vinegar to treat anemia and bleeding disorders. In Ayurveda, iron is used in a purified and processed form called Lauh Bhasma, prescribed for weakness, anemia, and menstrual disorders. Similarly, Traditional Chinese Medicine (TCM) utilized iron-rich herbs and mineral preparations to tonify the blood and strengthen Qi.
The understanding of iron's role in red blood cell formation emerged in the 19th and early 20th centuries, leading to the development of iron tonics and the widespread use of iron supplementation during pregnancy and for anemic conditions.
Today, iron remains a cornerstone nutrient in clinical and preventive medicine, with targeted use in anemia management, prenatal care, adolescent growth, recovery from blood loss, and sports nutrition. It is also monitored carefully to avoid iron overload (e.g., in hereditary hemochromatosis), as excessive iron can lead to oxidative stress and tissue damage.
Balanced iron intake is crucial for maintaining oxygen transport, energy production, and immune resilience—making it one of the most indispensable elements for human health.
Iron is used for these health conditions
Anemia (Scientific)
Appetite (deficient) (Scientific)
Attention Deficit Disorder (Scientific)
Body Building (Scientific)
Cancer Treatment (reducing side effects) (Scientific)
Circulation (poor) (Scientific)
Cold Hands and Feet (Scientific)
Convalescence (Scientific)
Fatigue (Scientific)
Fibroids (uterine) (Scientific)
Fingernails (weak or brittle) (Scientific)
Goiter (Scientific)
Hair (loss or thinning) (Scientific)
Heart (weakness) (Scientific)
Infertility (Scientific)
Labor and Delivery (Scientific)
Menorrhagia (Scientific)
Menstruation (scant) (Scientific)
Nursing (Scientific)
Oxygen Deficiency (Scientific)
Post Partum Weakness (Scientific)
Pregnancy (herbs and supplements for) (Scientific)
Restless Leg Syndrome (Scientific)
Sleep (restless and disturbed) (Scientific)
Surgery (healing from) (Scientific)
iron is used to support these body systems
Blood (Scientific)
Brain (Scientific)
Circulatory System (Scientific)
Digestive System (Scientific)
Glandular System (Scientific)
Hair (Scientific)
Heart (Scientific)
Immune System (Scientific)
Liver (Scientific)
Muscles (Scientific)
Nails (Scientific)
Nerves (Scientific)
Reproductive System (Scientific)
Spleen (Traditional)
Products containing iron
Vitabase
Active Man's Formula
Vitabase
Active Woman's Multi
Douglas Laboratories
Amino-Iron ™
Metagenics
Axis Endo™ Mango
Thorne
Basic Prenatal Multivitamin
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics
Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics
Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Collagenics®
Designs For Health
DFH Complete Multi™ with Copper & Iron
Vitabase
Easy Iron
Metagenics
Fem Prenatal®
Thorne
Ferrasorb
Designs For Health
Ferrochel® Iron Chelate
Metagenics
GI Sustain™ Powder
Douglas Laboratories
Hair, Skin and Nails Plus
Metagenics
Hemagenics
Metagenics
Hemagenics
Thorne
Iron Bisglycinate NSF
Pure Encapsulations
Iron-C
Integrative Therapeutics
Iron Complex
Integrative Therapeutics
K-PAX MitoNutrients
Metagenics
Ketogenic Shake Chocolate
Metagenics
Ketogenic Shake Vanilla
Klean Athlete
Klean Isolate™ Natural Chocolate Flavor
Klean Athlete
Klean Recovery ™
Pure Encapsulations
Liquid Iron
Integrative Therapeutics
Liquid Iron
Thorne
MediClear Plus
Metagenics
MetaKids Nutrition Powder Chocolate
Metagenics
MetaKids Nutrition Powder Vanilla
Pure Encapsulations
Mineral 650
Metagenics
Multigenics®
Metagenics
Multigenics Chewable Orange
Metagenics
Multigenics Intensive Care
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
Nutrient 950®
Pure Encapsulations
OptiFerin-C
Designs For Health
Organ Synergy™ 180 Capsules
Designs For Health
Organ Synergy™ Powder
Designs For Health
PaleoCleanse Plus™
Designs For Health
PaleoCleanse Plus™ Detox Program
Designs For Health
PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health
PaleoGreens®
Designs For Health
PaleoGreens®
Designs For Health
PaleoMeal®
Metagenics
Perfect Protein® Pea & Rice Chocolate Powder
Metagenics
Perfect Protein Pea & Rice Vanilla Powder
Metagenics
Perfect Protein Whey Chocolate
Integrative Therapeutics
Physicians Elemental Diet Dextrose Free
Integrative Therapeutics
Physician's Elemental Diet
Integrative Therapeutics
Physician's Elemental Diet
Integrative Therapeutics
Physicians Elemental Diet Kit
Metagenics
PhytoGanix® Tropical Fruit
Metagenics
PhytoMulti With Iron
Designs For Health
Phytotein™
Designs For Health
Plant Protein Cleanse
Designs For Health
Plant Protein Cleanse Plus™ 570g
Designs For Health
Plant Protein Meal
Designs For Health
Plant Protein Meal Plus
Designs For Health
Plant Protein Meal
Metagenics
PlusOne® Daily Prenatal Packs
Douglas Laboratories
Prenatal
Pure Encapsulations
PreNatal Nutrients
Pure Encapsulations
PreNatal Nutrients
Designs For Health
Prenatal Pro™
Pure Encapsulations
PureLean® Protein
Pure Encapsulations
PurePals with Iron
Designs For Health
PurePea™
Douglas Laboratories
Timed Release Iron
Metagenics
Ultra Calm® Bar Chocolate Coconut
Metagenics
Ultra Energy Bar Caramel Sea Salt
Metagenics
Ultra Glucose Control® Chocolate
Metagenics
Ultra Glucose Control Chocolate
Metagenics
Ultra Glucose Control Vanilla
Metagenics
Ultra Glucose Control Vanilla
Metagenics
Ultra Protein Bar Peanut Butter
Metagenics
UltraClear Detox Powder
Metagenics
UltraClear Plus® Detox Powder
Metagenics
UltraClear Plus Detox Powder Berry
Metagenics
UltraClear Plus Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics
UltraClear Plus pH Detox Powder Vanilla
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraInflamX Plus 360°® Chocolate/Orange
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Orange
Metagenics
UltraInflamX Plus 360° Original Spice
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraMeal Advanced Protein® Dutch Chocolate
Metagenics
UltraMeal Advanced Protein French Vanilla
Metagenics
UltraMeal Advanced Protein Plain
Metagenics
UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics
UltraMeal Cardio 360° Pea/Rice Vanilla
Metagenics
UltraMeal® Daily Support Dutch Chocolate
Metagenics
UltraMeal Daily Support Mixed Berry
Metagenics
UltraMeal Rice Vanilla
Metagenics
Wellness Essentials Women's Daily Packs
Thorne
Whey Protein Isolate Chocolate NSF
Designs For Health
WheyCool™
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