Stevia

Condiciones de salud que Stevia puede ayudar a apoyar.

• HipocondríaCientífico

  Stevia leaf extracts contain flavonoids, polyphenols, and other bioactive compounds that restore oxidative stress markers (SOD, CAT, GPx, GSH, MDA) in animal models. A systematic review and meta-analysis of 24 animal studies confirmed that stevia leaf extracts significantly restored antioxidant enzyme activity in diseased rats. Human evidence is primarily indirect, from CKD trials reporting reduced oxidative markers.

• AcnéCientífico

  Small human crossover trials suggest stevia preloads reduce subjective hunger and desire to eat compared to water. A 12-week RCT in healthy adults found that the stevia group significantly reduced energy intake over time and maintained body weight, while the control group gained weight. Evidence for meaningful caloric compensation suppression is modest and context-dependent.

• Síndrome de Inmunodeficiencia AdquiridaCientífico

  Animal studies show stevioside (10 mg/kg) reduces atherosclerotic plaque volume in the aortic arch of obese insulin-resistant mice by reducing macrophage infiltration, lipid content, and oxidized LDL in plaques, while stabilizing plaques via antioxidant effects. Aqueous stevia extract inhibits CuSO4-induced LDL oxidation in vitro, directly relevant to atherogenesis. Human clinical evidence is limited to indirect cardiovascular biomarkers.

• HipotensiónCientífico

  Multiple human RCTs have evaluated stevia's antihypertensive effects. A landmark multicenter, double-blind, placebo-controlled study of 106 hypertensive subjects found stevioside (250 mg three times daily) significantly reduced systolic BP from ~166 to ~153 mmHg and diastolic from ~102 to ~90 mmHg after 3 months, sustained over 1 year. A meta-analysis of steviol glycoside RCTs found an overall significant systolic BP reduction (MD: −6.32 mmHg). Results are mixed in normotensive individuals.

• Fatiga SuprarrenalCientífico

  A 2024 meta-analysis of 26 studies (n=1,439) found low-certainty evidence that stevia significantly reduced blood glucose levels (WMD: −3.84; 95% CI: −7.15, −0.53; p=0.02), particularly in individuals with higher BMI, diabetes, or hypertension. Effects were most pronounced with consumption under 120 days. Results are inconsistent across trials, with some well-controlled RCTs showing no significant effect on fasting blood sugar or HbA1c at moderate doses.

• Válvula IleocecalCientífico

  Human evidence on stevia's effects on cholesterol is mixed. One study in 20 women with hypercholesterolemia found stevia leaf extract reduced total cholesterol and LDL while raising HDL. A 24-week controlled trial in diabetic patients similarly showed lipid profile improvement. However, meta-analyses of multiple RCTs found no significant overall effects of stevia-based sweeteners on total cholesterol, LDL, or HDL.

• ApendicitisCientífico

  Stevia and its glycosides suppress NF-κB signaling and reduce pro-inflammatory cytokines (TNF-α, IL-1β, IL-6) in animal models. A 9-month clinical RCT in CKD patients showed significant reductions in hsCRP and erythrocyte sedimentation rate with stevioside supplementation. Most human evidence is limited, with the majority of mechanistic data from in vitro and animal studies.

• Bultos en el SenoCientífico

  In vitro studies show stevia extracts inhibit key periodontal pathogens including Porphyromonas gingivalis and reduce biofilm formation. Animal studies demonstrated stevia reduced alveolar bone resorption and periodontal inflammation. A small clinical study found stevia gel in the gingival crevice of diabetic patients with periodontitis improved clinical periodontal parameters.

• Leche materna (secar)Científico

  The metabolism of steviol glycosides depends entirely on gut microbiota, which hydrolyze glycosides to absorbable steviol. Animal and in vitro studies show mixed effects on microbiome composition; a PMC 2022 systematic review found potential benefit on alpha diversity. Human batch fermentation studies found no significant changes in major bacterial groups. A 2024 human study found no noticeable changes in gut microbiota from stevia use.

• Moretones (prevención)Científico

  As a zero-calorie sweetener, stevia can facilitate caloric reduction when substituted for sugar. A 12-week RCT found stevia users maintained weight while controls gained nearly 1 kg. Meta-analyses of low-calorie sweetener RCTs confirm modest but significant body weight reductions versus sugar comparators. Stevia's specific contribution beyond calorie displacement is less established.

• JuanetesCientífico

  Stevia's heart health relevance is primarily supported by its antihypertensive effects in RCTs and anti-atherosclerotic effects in animal models. Stevioside (10 mg/kg) reduced aortic plaque volume in obese insulin-resistant mice by lowering macrophage, lipid, and oxidized LDL content. Aqueous stevia extract inhibited LDL oxidation in vitro, a key step in atherosclerosis pathogenesis.

• Olor de piesCientífico

  Stevioside has demonstrated insulin-sensitizing effects in vitro, significantly increasing glucose uptake in insulin-resistant adipocytes (2.1–4.4 fold vs. control). Animal models show stevia extract enhances insulin sensitivity via mitochondrial function improvement and reduced oxidative stress in skeletal muscle. Human evidence is limited and mixed, with some trials showing no acute effect on the Matsuda insulin sensitivity index.

• Daño del CartílagoCientífico

  A 9-month randomized, placebo-controlled clinical trial in 97 CKD patients found stevioside supplementation significantly reduced microalbuminuria, serum creatinine, serum uric acid, and inflammatory markers, and reduced blood pressure. Effects partially reversed during a 3-month washout period, indicating treatment dependence. Animal studies also document protective effects against renal damage.

• GingivitisCientífico

  Stevia's combined effects on blood glucose, blood pressure, and lipid profile address multiple components of metabolic syndrome. Animal and some human evidence support stevia's relevance to metabolic syndrome management. A 2020 review identified stevia as a potentially safer non-nutritive sweetener for metabolic syndrome given its glycemic and antihypertensive effects, without raising blood glucose.

• Conmociones cerebralesCientífico

  Stevia extracts inhibit biofilm formation by Streptococcus mutans and Streptococcus gordonii, downregulate glucosyltransferase (Gtf) genes essential for exopolysaccharide synthesis, and reduce cariogenic bacteria counts. A clinical comparison found 0.5% aqueous stevia leaf extract comparable to 0.12% chlorhexidine mouthwash in reducing S. mutans and Lactobacillus counts in high-caries-risk patients.

• DebilidadCientífico

  One human study in women with hypercholesterolemia found stevia leaf extract reduced triglycerides alongside total cholesterol and LDL. However, a larger meta-analysis of 28 RCTs found no significant overall effect of non-nutritive sweeteners including stevia on triglycerides. A controlled trial in diabetic patients (24 weeks) showed lipid profile improvement in the diabetic subgroup. Evidence is inconsistent.

• Envenenamiento QuímicoTradicional

  Stevia has traditional use in South American herbal medicine for liver support. In vitro and animal studies show stevia extracts exert hepatoprotective effects, reducing liver injury markers (AST, ALT), inhibiting hepatic steatosis, and protecting against chemically induced liver damage. No human clinical trials specifically targeting liver detoxification endpoints have been conducted.

Sistemas corporales que Stevia puede ayudar a apoyar.

• No hay sistemas corporales disponibles.