Enicostemma littorale

Condiciones de salud que Enicostemma littorale puede ayudar a apoyar.

• HipocondríaCientífico

  E. littorale extracts and its isolated compound swertiamarin demonstrate significant antioxidant activity in multiple in vitro and in vivo models, including upregulation of superoxide dismutase, catalase, glutathione peroxidase, and glutathione-S-transferase. A preliminary clinical study in NIDDM patients also found significant improvement in antioxidant parameters after two months of treatment.

• EccemaCientífico

  E. littorale methanolic extract demonstrated significant analgesic and anti-arthritic activity in Freund's adjuvant-induced arthritis in rats, reducing paw volume and elevating antioxidant enzymes. Traditional systems (Siddha, Ayurveda) also document its use for rheumatism. Preclinical evidence is consistent with an anti-inflammatory mechanism via antioxidant pathways.

• HipotensiónCientífico

  The clinical trial in 84 T2D patients treated with E. littorale pills for three months showed significant reductions in systolic and diastolic blood pressure as well as pulse rate. Animal studies also support antihypertensive-related effects, and a cardiac hypertrophy model showed cardiovascular normalization comparable to the reference drug losartan.

• Fatiga SuprarrenalCientífico

  Multiple clinical and preclinical studies confirm E. littorale lowers fasting and postprandial blood glucose in type 2 diabetic patients and animal models. A published clinical trial in 84 T2D patients showed significant reductions in blood glucose and serum insulin after three months. The key mechanism involves insulinotropic activity at pancreatic islets via a K⁺-ATP channel-dependent pathway.

• Válvula IleocecalCientífico

  E. littorale and its isolated compound swertiamarin have demonstrated significant lipid-lowering effects in preclinical models, including reduction of total cholesterol, LDL, and VLDL with elevation of HDL in hypercholesterolaemic rats. Swertiamarin inhibits HMG-CoA reductase at a level comparable to atorvastatin in animal studies. The human clinical trial in 84 T2D patients also documented significant improvement in lipid profile.

• ApendicitisCientífico

  E. littorale aerial parts exhibit documented anti-inflammatory activity in validated preclinical models including BSA protein denaturation, Freund's adjuvant arthritis, and in vitro TNF-α/IL-6 inhibition assays. Swertiamarin supplementation has also been shown to prevent obesity-related chronic inflammation in high-fat diet mouse models.

• Olor de piesCientífico

  Swertiamarin, the principal secoiridoid glycoside isolated from E. littorale, has been shown to improve insulin sensitivity in NIDDM rat models by targeting PPAR-γ and modulating key metabolic genes. Animal studies demonstrate restoration of glucose transporter expression and normalization of hepatic and adipose tissue gene profiles associated with insulin resistance.

• Daño del CartílagoCientífico

  E. littorale treatment in 84 T2D patients produced significant improvement in kidney function parameters over three months. Animal studies confirm nephroprotective activity and reduction of renal cholesterol and triglyceride accumulation. In vivo nephroprotection data and clinical kidney function normalization are both documented.

• Envenenamiento QuímicoCientífico

  E. littorale demonstrates hepatoprotective and hepatomodulatory activity in multiple preclinical models including paracetamol-, D-galactosamine-, ethanol-, and CCl4-induced hepatotoxicity. Swertiamarin is identified as the primary hepatoprotective phytochemical, with mechanisms including antioxidant enzyme upregulation, ROS reduction, and normalization of hepatic biomarker enzymes.

• GingivitisCientífico

  E. littorale and swertiamarin address multiple components of metabolic syndrome simultaneously: hyperglycaemia, dyslipidaemia, insulin resistance, hypertension, and obesity—all demonstrated in preclinical models and partially in a human diabetic cohort. The PPAR-γ-targeting mechanism of swertiamarin is particularly relevant to metabolic syndrome pathophysiology.

• Dolor de cabeza (tensión)Científico

  The same Freund's adjuvant preclinical study that characterized anti-arthritic activity explicitly evaluated and proposed E. littorale as a candidate for rheumatoid arthritis control, based on reduced paw edema and antioxidant protection. Traditional use across Siddha and Ayurveda for rheumatism (Vata disease) is well-documented.

• DebilidadCientífico

  Multiple preclinical studies confirm E. littorale and swertiamarin significantly reduce serum and tissue triglycerides in hyperlipidaemic and diabetic animal models. The human trial in 84 T2D patients reported improved lipid profile including triglyceride reduction. Swertiamarin's inhibition of SREBP-1c and HMG-CoA reductase are among the implicated mechanisms.

• Hernia HiatalCientífico

  Methanolic and aqueous aerial part extracts of E. littorale showed dose-dependent antiulcer activity in aspirin-, ethanol-, and pyloric ligation-induced ulcer rat models. The extract reduced ulcer index, total acidity, free acidity, and volume of gastric secretion while elevating gastric pH. Traditional Siddha medicine also uses the plant specifically for abdominal ulcers.

• DislocaciónTradicional

  E. littorale is traditionally used in Ayurveda, Siddha, and Unani systems as a stomachic, carminative, and remedy for abdominal disorders. Its bitter properties are considered to stimulate digestive function. These uses are well-documented in classical texts and ethnobotanical records but lack dedicated human clinical trials.

• AcnéTradicional

  E. littorale is traditionally described as a tonic for appetite loss and as a stomachic bitter in Ayurveda and Indian folk medicine. Its bitter taste quality (Tikta rasa) is the classical pharmacological basis for this use in the Ayurvedic system. No controlled clinical evidence for appetite modulation is available.

• ArtritisTradicional

  E. littorale is described as a laxative in Ayurvedic and Siddha texts, and this property is cited consistently across pharmacognosy reviews. It is used in traditional practice for constipation and is classified as having laxative properties in its Ayurvedic categorization. No clinical laxative trials have been conducted.

• Vista (deficiente)Tradicional

  E. littorale is used in traditional Indian medicine for skin diseases including eczema, itching, and skin disorders associated with Pitta imbalance in Ayurveda. It is documented in Siddha medicine for skin diseases (Pitta diseases) and mentioned in folk medicine for eczema. No clinical dermatology trials have been published.

• Sangrado (interno)Tradicional

  E. littorale is classified as an antipyretic (febrifuge) in Ayurveda, Siddha, and Unani systems, and this is documented in multiple pharmacognosy reviews. It has been used as a bitter tonic for fever reduction in Indian traditional medicine for centuries. Published human antipyretic clinical data are not available.

• Moretones (prevención)Tradicional

  E. littorale is documented in Siddha medicine for obesity, and Ayurvedic texts identify its main site of action as medodhatu (adipose tissue), with anti-obesity properties noted. Preclinical anti-obesity data exist, and swertiamarin supplementation has been shown to prevent obesity-related chronic inflammation in high-fat diet mice. Clinical weight management trials are lacking.

• DifteriaTradicional

  Wound healing is documented as a traditional use of E. littorale in Indian folk medicine and Siddha practice, and the plant is listed in the Ayurvedic disease category that includes wound healing. A Siddha herbal wound formulation containing E. littorale was reported to fully heal cattle wounds within 4–7 days in a preliminary observation.

Sistemas corporales que Enicostemma littorale puede ayudar a apoyar.

• No hay sistemas corporales disponibles.